Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics - Perepelyuk, Maryna; Chin, LiKang; Cao, Xuan; van Oosten, Anne; Shenoy, Vivek B.; Janmey, Paul A.; Wells, Rebecca G. (PLOS ONE, 2016)
Keywords: Animal models; Animals; Bioengineering; Care and treatment; Collagen; Complications and side effects; Compressibility; Compression; Compressive Strength; Development and progression; Engineering schools; Extracellular matrix; Fibrosis; Glycosaminoglycans; Glycosaminoglycans - analysis; Growth factors; In Vitro Techniques; Incompressibility; Legal medicine; Liver; Liver - physiology; Liver Cirrhosis, Experimental; Liver Cirrhosis, Experimental - chemically induced; Liver Cirrhosis, Experimental - physiopathology; Liver diseases; Loss modulus; Materials science; Mathematical analysis; Matrix methods; Mechanical analysis; Mechanical properties; Mechanics; Mechanics (physics); Medicine; Models, Biological; Modulus of elasticity; Patient outcomes; Physiology; Plastic deformation; Q; R; Rats; Rats, Sprague-Dawley; Research Article; Rheometry; Rodents; Science; Shear modulus; Shear strain; Shear Strength; Softening; Stiffening; Stiffness; Strain; Stress (physiology); Stress, Mechanical; Tissues; Viscoelasticity; Water flow; United States