Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery - Blundell, Tom L; Sibanda, Bancinyane L; Montalvão, Rinaldo Wander; Brewerton, Suzanne; Chelliah, Vijayalakshmi; Worth, Catherine L; Harmer, Nicholas J; Davies, Owen; Burke, David (Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2006)
Keywords: Bioinformatics; Computational Biology; Crystallography; Drug Design; Drug discovery; Drug Evaluation, Preclinical; Drug interactions; Genomics; High-Throughput Crystallography; Humans; Lead; Ligands; Molecules; Multiprotein Complexes; Protein Conformation; Proteins; Structural Bioinformatics; Structural Biology; Structure-Based Drug Design; Substrate Specificity; Virtual Screening