The persistence of atopic dermatitis and filaggrin (FLG) mutations in a US longitudinal cohort - Margolis, David J.; Apter, Andrea J.; Gupta, Jayanta; Hoffstad, Ole; Papadopoulos, Maryte; Campbell, Linda E.; Sandilands, Aileen; McLean, W.H. Irwin; Rebbeck, Tim R.; Mitra, Nandita (Journal of allergy and clinical immunology, 2012)
Keywords: African Americans; Allergic diseases; Allergies; Allergy and Immunology; ancestry; Asthma; Atopic dermatitis; atopy; Biological and medical sciences; Child, Preschool; Children; Cohort Studies; Dermatitis, Atopic - drug therapy; Dermatitis, Atopic - genetics; drug therapy; epidemiology; Female; Filaggrin; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Genes; genetic epidemiology; Humans; Immunopathology; Infant; Intermediate Filament Proteins - genetics; Longitudinal Studies; Male; Medical sciences; Medical treatment; Mutation; odds ratio; Pathogenesis; Polymorphism, Single Nucleotide; Population; pruritus; risk; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Skin allergic diseases. Stinging insect allergies; Skin diseases; Studies; United States; United States; North America; America; United States--US; FLG; epidemiology; AD; OR; Atopic dermatitis; AIM; PEER; atopy; ALSPAC; FLG null; filaggrin; genetic epidemiology; Pediatric Eczema Elective Registry; Filaggrin loss of function; Avon Longitudinal Study of Parents and Children; Ancestry informative marker; Odds ratio; Allergy; Immunopathology; Skin disease; Filaggrin; Epidemiology; Atopy; Persistence; Immunology; Epidemiologic genetics; Cohort study; Mutation