Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases - Li, Xingnan; Ampleford, Elizabeth J.; Howard, Timothy D.; Moore, Wendy C.; Torgerson, Dara G.; Li, Huashi; Busse, William W.; Castro, Mario; Erzurum, Serpil C.; Israel, Elliot; Nicolae, Dan L.; Ober, Carole; et al. (Journal of allergy and clinical immunology, 2012)
Keywords: alleles; Allergy and Immunology; Asthma; Asthma - etiology; Asthma - genetics; Asthma - immunology; Autoimmune diseases; Autoimmune Diseases - etiology; Autoimmune Diseases - genetics; Autoimmune Diseases - immunology; Biological and medical sciences; Chronic obstructive pulmonary disease, asthma; colitis; Crohn disease; Crohn's disease; Cytokines; Disease; DNA-Binding Proteins - genetics; Fundamental and applied biological sciences. Psychology; Fundamental immunology; genetics; Genome-Wide Association Study; Genomes; Histocompatibility antigen HLA; Humans; Immune system; Immunopathogenesis; Immunopathology; Inflammation; Inflammatory bowel disease; Interleukin 1; Interleukin 13; Interleukin 18 receptors; interleukin-18; lupus erythematosus; Medical sciences; Pneumology; Polymorphism, Single Nucleotide; Population; Psoriasis; Quality control; Research programs; Rheumatoid arthritis; risk; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; sclerosis; Single-nucleotide polymorphism; Studies; Systemic lupus erythematosus; Systemic sclerosis; Thymic stromal lymphopoietin; TNFAIP3 interacting protein 1; transcription factor NF-kappa B; Ulcerative colitis; Whites; TENOR; GSDMB; WDR36; GWAS; OR; TSLP; CAG; SARP; SLE; Asthma; IL18R; IL1RL1; genetics; SNP; TNIP1; CSGA; genome-wide association study; ORMDL3; LD; TNFAIP3 interacting protein 1; IL-1 receptor–like 1; Linkage disequilibrium; WD repeat domain 36; Systemic lupus erythematosus; ORM1-like 3; Chicago Asthma Genetics Study; Collaborative Studies on the Genetics of Asthma; IL-18 receptor 1; Severe Asthma Research Program; Thymic stromal lymphopoietin; The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens; Gasdermin B; Odds ratio; Single nucleotide polymorphism; Lung disease; Immunopathology; Respiratory disease; Autoimmune disease; Protein; Association; Immunology; Bronchus disease; Genetics; Obstructive pulmonary disease; Genome