血清炎性因子联合NIHSS评分评价急性缺血性卒中患者病情的临床研究
目的探讨急性缺血性卒中患者血清炎性因子及美国国立卫生研究院卒中量表(NIHSS)评分变化对病情评价的临床意义。方法分别检测90例急性缺血性卒中患者治疗前后血清白细胞介素6(IL 6)、肿瘤坏死因子α(TNFα)、超敏C反应蛋白(hs CRP)水平和NIHSS评分变化,并与正常对照受试者进行比较。结果根据梗死灶体积将患者分为大型(>10 cm3)、中型(5~10 cm3)和小型(<5 cm3)共3个亚组,治疗前3组患者血清IL 6、TNFα和hs CRP水平均高于正常对照组(P<0.01),治疗后各项炎性因子和NIHSS评分降低,与治疗前差异仍有统计学意...
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| Published in | 中国现代神经疾病杂志 Vol. 13; no. 9; pp. 801 - 804 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
400030,重庆市沙坪坝区人民医院急诊科%400016,重庆医科大学附属第一医院神经内科
2013
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1672-6731 |
| DOI | 10.3969/j.issn.1672-6731.2013.09.014 |
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| Abstract | 目的探讨急性缺血性卒中患者血清炎性因子及美国国立卫生研究院卒中量表(NIHSS)评分变化对病情评价的临床意义。方法分别检测90例急性缺血性卒中患者治疗前后血清白细胞介素6(IL 6)、肿瘤坏死因子α(TNFα)、超敏C反应蛋白(hs CRP)水平和NIHSS评分变化,并与正常对照受试者进行比较。结果根据梗死灶体积将患者分为大型(>10 cm3)、中型(5~10 cm3)和小型(<5 cm3)共3个亚组,治疗前3组患者血清IL 6、TNFα和hs CRP水平均高于正常对照组(P<0.01),治疗后各项炎性因子和NIHSS评分降低,与治疗前差异仍有统计学意义(均P<0.01)。结论血清炎性因子水平和NIHSS评分可作为急性缺血性卒中患者的病情评价和疗效监测指标。 |
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| AbstractList | 目的探讨急性缺血性卒中患者血清炎性因子及美国国立卫生研究院卒中量表(NIHSS)评分变化对病情评价的临床意义。方法分别检测90例急性缺血性卒中患者治疗前后血清白细胞介素6(IL 6)、肿瘤坏死因子α(TNFα)、超敏C反应蛋白(hs CRP)水平和NIHSS评分变化,并与正常对照受试者进行比较。结果根据梗死灶体积将患者分为大型(>10 cm3)、中型(5~10 cm3)和小型(<5 cm3)共3个亚组,治疗前3组患者血清IL 6、TNFα和hs CRP水平均高于正常对照组(P<0.01),治疗后各项炎性因子和NIHSS评分降低,与治疗前差异仍有统计学意义(均P<0.01)。结论血清炎性因子水平和NIHSS评分可作为急性缺血性卒中患者的病情评价和疗效监测指标。 目的 探讨急性缺血性卒中患者血清炎性因子及美国国立卫生研究院卒中量表(NIHSS)评分变化对病情评价的临床意义.方法 分别检测90例急性缺血性卒中患者治疗前后血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超敏C-反应蛋白(hs-CRP)水平和NIHSS评分变化,并与正常对照受试者进行比较.结果 根据梗死灶体积将患者分为大型(＞10 cm 3)、中型(5～10cm 3)和小型(＜5cm3)共3个亚组,治疗前3组患者血清IL-6 、TNF-α和hs-CRP水平均高于正常对照组(P＜0.01),治疗后各项炎性因子和NIHSS评分降低,与治疗前差异仍有统计学意义(均P＜0.01).结论 血清炎性因子水平和NIHSS评分可作为急性缺血性卒中患者的病情评价和疗效监测指标. |
| Author | 喻恒 龙崇荣 王亮 |
| AuthorAffiliation | 重庆市沙坪坝区人民医院急诊科;重庆医科大学附属第一医院神经内科 |
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| Author_FL | LONG Chong-rong YU Heng WANG Liang |
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| Keywords | 肿瘤坏死因子α Tumor necrosis factor-alpha 脑缺血 C-reactive protein 白细胞介素6 Brain ischemia C反应蛋白质 Interleukin-6 |
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| Notes | YU Heng;LONG Chong rong;WANG Liang;Department of Emergency, Chongqing Shapingba District People’s Hospital;Department of Neurology, the First Affiliated Hospital of Chongqing Medical University 12-1363/R |
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| Publisher | 400030,重庆市沙坪坝区人民医院急诊科%400016,重庆医科大学附属第一医院神经内科 |
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| Snippet | 目的探讨急性缺血性卒中患者血清炎性因子及美国国立卫生研究院卒中量表(NIHSS)评分变化对病情评价的临床意义。方法分别检测90例急性缺血性卒中患者治疗前后血清白细胞介素6(IL 6)、肿瘤坏死因子α(TNFα)、超敏C反应蛋白(hs... 目的 探讨急性缺血性卒中患者血清炎性因子及美国国立卫生研究院卒中量表(NIHSS)评分变化对病情评价的临床意义.方法 分别检测90例急性缺血性卒中患者治疗前后血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超敏C-反应蛋白(hs-CRP)水平和NIHSS评分变化,并与正常对照受试者进行比较.结果... |
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| SubjectTerms | 脑缺血;白细胞介素6;肿瘤坏死因子α;C反应蛋白质 |
| Title | 血清炎性因子联合NIHSS评分评价急性缺血性卒中患者病情的临床研究 |
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