Anti-Inflammatory and Immunosuppressive Effects of the A 2A Adenosine Receptor

• Published in: TheScientificWorld Vol. 11; pp. 320 - 339
• Main Authors: Milne, Gillian R., Palmer, Timothy M.
• Format: Journal Article
• Language: English
• Published: 2011

The production of adenosine represents a critical endogenous mechanism for regulating immune and inflammatory responses during conditions of stress, injury, or infection. Adenosine exerts predominantly protective effects through activation of four 7-transmembrane receptor subtypes termed A 1 , A 2A...