Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning

• Published in: Science (American Association for the Advancement of Science) Vol. 304; no. 5669; pp. 452 - 454
• Main Authors: O'Doherty, John, Dayan, Peter, Schultz, Johannes, Deichmann, Ralf, Friston, Karl, Dolan, Raymond J.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Association for the Advancement of Science 16.04.2004; The American Association for the Advancement of Science
• Subjects: Adult; Animals; Basal ganglia; Basal Ganglia - physiology; Behavioral neuroscience; Biological and medical sciences; Brain; Brain chemistry; Caudate Nucleus - physiology; Classical Conditioning; Computers; Conditioning, Classical; Conditioning, Operant; Coordinate systems; Environment; Error signals; Experimentation; Feedback (Response); Female; Fundamental and applied biological sciences. Psychology; Hemispheres; Human subjects; Humans; Learning; Magnetic Resonance Imaging; Male; Middle Aged; Neurons; Nucleus accumbens; Nucleus Accumbens - physiology; Observations; Operant Conditioning; Physiological aspects; Probability; Putamen; Putamen - physiology; Reinforcement (Psychology); Reward; Stimuli; Vertebrates: nervous system and sense organs; United Kingdom; Learning; Human; Acquisition process; Central nervous system; Reinforcement; Instrumental conditioning; Basal ganglion; Corpus striatum; Models; Nuclear magnetic resonance imaging; Encephalon

Instrumental conditioning studies how animals and humans choose actions appropriate to the affective structure of an environment. According to recent reinforcement learning models, two distinct components are involved: a "critic," which learns to predict future reward, and an "actor,&...