Giant lungfish genome elucidates the conquest of land by vertebrates

• Published in: Nature (London) Vol. 590; no. 7845; pp. 284 - 289
• Main Authors: Meyer, Axel, Schloissnig, Siegfried, Franchini, Paolo, Du, Kang, Woltering, Joost M., Irisarri, Iker, Wong, Wai Yee, Nowoshilow, Sergej, Kneitz, Susanne, Kawaguchi, Akane, Fabrizius, Andrej, Xiong, Peiwen, Dechaud, Corentin, Spaink, Herman P., Volff, Jean-Nicolas, Simakov, Oleg, Burmester, Thorsten, Tanaka, Elly M., Schartl, Manfred
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 11.02.2021; Nature Publishing Group
• Subjects: 38/23; 45; 631/181/2474; 631/181/757; 631/208/182; 631/208/212/2304; Adaptation, Physiological - genetics; Air; Analysis; Animal Fins - anatomy & histology; Animals; Bayes Theorem; Biological Evolution; Chromosomes; Chromosomes - genetics; Datasets; Deoxyribonucleic acid; Devonian; DNA; Evolution; Evolutionary genetics; Extremities - anatomy & histology; Female; Fins; Fish; Fishes - genetics; Fishes - physiology; Gait - genetics; Gene expression; Gene Expression Regulation, Developmental; Gene families; Genes; Genes, Homeobox - genetics; Genetic aspects; Genome - genetics; Genomes; Genomics; Homology; Humanities and Social Sciences; Humans; Identification and classification; Introns; Karyotypes; Long Interspersed Nucleotide Elements - genetics; Lung - anatomy & histology; Lung - physiology; Lung-fishes; Lungs; Mice; Molecular Sequence Annotation; Morphology; multidisciplinary; Odors; Phylogeny; Pollutants; Proteins; Respiration; Science; Science (multidisciplinary); Smell - physiology; Surfactants; Synteny; Transposons; Vertebrates; Vertebrates - genetics; Vertebrates - physiology; Vomeronasal Organ - anatomy & histology; Australia; Germany

Lungfishes belong to lobe-fined fish (Sarcopterygii) that, in the Devonian period, ‘conquered’ the land and ultimately gave rise to all land vertebrates, including humans 1 – 3 . Here we determine the chromosome-quality genome of the Australian lungfish ( Neoceratodus forsteri ), which is known to h...