Levels of Porphyromonas gingivalis Fimbriae and Inflammatory Cytokines in Gingival Crevicular Fluid from Adult Human Subjects

• Published in: MICROBIOLOGY and IMMUNOLOGY Vol. 41; no. 1; pp. 21 - 26
• Main Authors: Hirose, Kimiharu, Isogai, Emiko, Miura, Hiroko, Ueda, Itsuo
• Format: Journal Article
• Language: English
• Published: Tokyo Blackwell Publishing Ltd 1997; Center For Academic Publications Japan; Center for Academic Publications Japan
• Subjects: Adult; Adult periodontitis; Bacteriology; Biological and medical sciences; Female; Fimbriae; Fimbriae, Bacterial - metabolism; Fundamental and applied biological sciences. Psychology; Gingival Crevicular Fluid - metabolism; Gingival Crevicular Fluid - microbiology; Humans; Inflammation; Inflammatory cytokine; Interleukin-1 - metabolism; Interleukin-6 - metabolism; Male; Microbiology; Middle Aged; Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains; Periodontal Pocket - metabolism; Periodontal Pocket - microbiology; Porphyromonas gingivalis; Porphyromonas gingivalis - metabolism; Tumor Necrosis Factor-alpha - metabolism; Human; Porphyromonas gingivalis; Stomatology; Cytokine; Interleukin 1α; Host agent relation; Interleukin 1β; Pilus; Inflammation; Bacteroidaceae; Infection; Interleukin 6; Periodontal disease; Periodontitis; Bacteriosis; Bacteria; Tumor necrosis factor α; Quantitative analysis; Gingival fluid
• ISSN: 0385-5600; 1348-0421
• DOI: 10.1111/j.1348-0421.1997.tb01168.x

The Porphyromonas gingivalis fimbriae level was examined in the gingival crevicular fluid (GCF) from adult human subjects using an immunoblot assay with a monoclonal antibody. The cytokines, interleukin-1α (IL-1α), IL-1β, IL-6 and tumor necrosis factor-α (TNF-α) levels in the GCF were quantified by...