Expression of CYP2W1 in the adrenal gland: relationship with hormone secretion and clinical outcome

• Published in: Experimental and Clinical Endocrinology & Diabetes
• Main Authors: Ronchi, CL, Sbiera, S, Volante, M, Steinhauer, S, Wild-Scott, V, Kroiss, M, Papotti, M, Deutschbein, T, Terzolo, M, Fassnacht, M, Allolio, B
• Format: Conference Proceeding
• Language: English
• Published: 05.03.2014

Adrenocortical tumors consist of frequent adenomas (ACA) and rare highly malignant carcinomas (ACC). The orphan enzyme cytochrome P450 2W1 (CYP2W1) is selectively expressed in some cancers and represent a promising new drug target in cancer therapy. CYP2W1 mRNA levels were analyzed in 58 frozen samp...