HDL particle morphology in Alzheimer’s disease patients compared to healthy human subjects and chemically modified HDL

• Published in: Alzheimer's & dementia Vol. 17; no. S5
• Main Authors: Zheng, Jack Jingyuan, Hong, Brian V., Agus, Joanne, Guo, Fei, Cavicchi, Richard E., Jin, Lee‐Way, Maezawa, Izumi, Lebrilla, Carlito B., Harvey, Danielle J., Zivkovic, Angela M.
• Format: Journal Article
• Language: English
• Published: 01.12.2021

Background In various chronic diseases including Alzheimer’s disease, a common clinical manifestation is defective high‐density lipoprotein (HDL) status. Published evidence suggests that HDL particles from Alzheimer’s patients are functionally deficient, as measured by impaired cholesterol efflux ca...