Accumulation of succinate controls activation of adipose tissue thermogenesis - Mills, Evanna L.; Pierce, Kerry A.; Jedrychowski, Mark P.; Garrity, Ryan; Winther, Sally; Vidoni, Sara; Yoneshiro, Takeshi; Spinelli, Jessica B.; Lu, Gina Z.; Kazak, Lawrence; Banks, Alexander S.; Haigis, Marcia C.; et al. (Nature (London), 2018)
Keywords: 631/45/320; 631/80/304; 64; 64/60; 82; 82/1; 82/16; 82/58; 82/80; 96/1; 96/106; 96/98; Accumulation; Activation; Adipocytes; Adipocytes - drug effects; Adipocytes - enzymology; Adipocytes - metabolism; Adipose tissue; Adipose tissue (brown); Adipose Tissue, Brown - cytology; Adipose Tissue, Brown - drug effects; Adipose Tissue, Brown - enzymology; Adipose Tissue, Brown - metabolism; Adipose Tissue, White - cytology; Adipose Tissue, White - drug effects; Adipose Tissue, White - enzymology; Adipose Tissue, White - metabolism; Animals; Body fat; Control; Cyclic adenosine monophosphate; Cyclic AMP; Dehydrogenase; Dehydrogenases; Energy; External stimuli; Female; Glucose; Glucose tolerance; Humanities and Social Sciences; Hypotheses; Kinases; Letter; Lipolysis; Male; Metabolic disorders; Metabolism; Metabolites; Metabolomics; Mice; multidisciplinary; Obesity - metabolism; Obesity - prevention & control; Oxidation; Oxidation-Reduction - drug effects; Oxidation-reduction reactions; Oxygen; Pharmacology; Physiological aspects; Protein kinase A; Protein kinases; Proteins; Reactive oxygen species; Reactive Oxygen Species - metabolism; Respiration; Rodents; Science; Science (multidisciplinary); Signal transduction; Signaling; Succinate dehydrogenase; Succinate Dehydrogenase - metabolism; Succinates; Succinic Acid - metabolism; Succinic Acid - pharmacology; Thermogenesis; Thermogenesis - drug effects; Thermogenesis - physiology; Tricarboxylic acid cycle; Uncoupling Protein 1 - metabolism