Effects of DPP‐4 inhibitor linagliptin and GLP‐1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: A randomized, open‐label, 2‐arm parallel comparative, exploratory trial - Yabe, Daisuke; Eto, Takashi; Shiramoto, Masanari; Irie, Shin; Murotani, Kenta; Seino, Yusuke; Kuwata, Hitoshi; Kurose, Takeshi; Seino, Susumu; Ahrén, Bo; Seino, Yutaka (Diabetes, obesity & metabolism, 2017)
Keywords: Aged; Antidiabetics; Brief Report; Brief Reports; Clinical Medicine; Diabetes; Diabetes Mellitus, Type 2 - drug therapy; Dipeptidyl-peptidase IV; Dipeptidyl-Peptidase IV Inhibitors - therapeutic use; DPP-4 inhibitor; Endocrinology and Diabetes; Endokrinologi och diabetes; Epinephrine - metabolism; Evidence-based medicine; Female; GLP-1 receptor agonist; GLP-1 receptor agonists; Glucagon - metabolism; Glucagon response; Glucagon-Like Peptide-1 Receptor - agonists; Glucose; Glucose Clamp Technique; Human Growth Hormone - metabolism; Humans; Hydrocortisone - metabolism; Hypoglycaemia; Hypoglycemia; Hypoglycemia - metabolism; Hypoglycemic Agents - therapeutic use; Japan; Klinisk medicin; Linagliptin - therapeutic use; Liraglutide - therapeutic use; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Middle Aged; Norepinephrine - metabolism; Sympatho-adrenal response; glucagon response; sympatho-adrenal response; GLP-1 receptor agonist; hypoglycaemia; DPP-4 inhibitor