Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer’s disease - Cicognola, Claudia; Brinkmalm, Gunnar; Wahlgren, Jessica; Portelius, Erik; Gobom, Johan; Cullen, Nicholas C.; Hansson, Oskar; Parnetti, Lucilla; Constantinescu, Radu; Wildsmith, Kristin; Chen, Hsu-Hsin; Beach, Thomas G.; et al. (Acta neuropathologica, 2019)
Keywords: Advertising executives; Aged; Alzheimer Disease - cerebrospinal fluid; Alzheimer Disease - metabolism; Alzheimer Disease - pathology; Alzheimer's disease; Amino acids; Amyloid beta-Peptides - cerebrospinal fluid; Amyloid beta-Peptides - metabolism; Antibodies; Antigenic determinants; Biomarkers - cerebrospinal fluid; Brain - metabolism; Brain - pathology; Cerebrospinal fluid; Clinical Medicine; Cognitive ability; Cognitive Dysfunction - cerebrospinal fluid; Cognitive Dysfunction - metabolism; Cognitive Dysfunction - pathology; Cohort Studies; Enzyme inhibitors; Epitopes; Female; Humans; Immunoassay; Immunohistochemistry; Klinisk medicin; Male; Mass spectrometry; Mass spectroscopy; Medical and Health Sciences; Medical schools; Medicin och hälsovetenskap; Medicine; Medicine & Public Health; Neurofibrillary tangles; Neurologi; Neurology; Neurons; Neurophysiology; Neuropil; Neurosciences; Neurovetenskaper; Original Paper; Pathology; Patients; Peptide Fragments - cerebrospinal fluid; Peptides; Protein binding; Spectroscopy; Tau fragments; Tau protein; tau Proteins - cerebrospinal fluid; tau Proteins - metabolism; Tau fragments; Immunohistochemistry; Cerebrospinal fluid; Alzheimer’s disease; Mass spectrometry