Amygdalar nuclei and hippocampal subfields on MRI: Test-retest reliability of automated volumetry across different MRI sites and vendors

• Published in: NeuroImage Vol. 218; p. 116932
• Main Authors: Quattrini, Giulia, Pievani, Michela, Jovicich, Jorge, Aiello, Marco, Bargalló, Núria, Barkhof, Frederik, Bartres-Faz, David, Beltramello, Alberto, Pizzini, Francesca B., Blin, Olivier, Bordet, Regis, Caulo, Massimo, Constantinides, Manos, Didic, Mira, Drevelegas, Antonios, Ferretti, Antonio, Fiedler, Ute, Floridi, Piero, Gros-Dagnac, Hélène, Hensch, Tilman, Hoffmann, Karl-Titus, Kuijer, Joost P., Lopes, Renaud, Marra, Camillo, Müller, Bernhard W., Nobili, Flavio, Parnetti, Lucilla, Payoux, Pierre, Picco, Agnese, Ranjeva, Jean-Philippe, Roccatagliata, Luca, Rossini, Paolo M., Salvatore, Marco, Schonknecht, Peter, Schott, Björn H., Sein, Julien, Soricelli, Andrea, Tarducci, Roberto, Tsolaki, Magda, Visser, Pieter J., Wiltfang, Jens, Richardson, Jill C., Frisoni, Giovanni B., Marizzoni, Moira
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2020; Elsevier BV; Elsevier Limited; Elsevier
• Subjects: [SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging; Adult; Aged; ALZHEIMERS-DISEASE; Amygdala; Amygdala - anatomy & histology; Amygdalar nuclei; Amygdalar nuclei; FreeSurfer; Hippocampal subfields; Multicenter MRI study; Reliability analysis; Amygdalar nuclei; Hippocampal subfields; Multicenter MRI study; FreeSurfer; Reliability analysis; anatomy & histology [Amygdala]; anatomy & histology [Hippocampus]; Automation; Behavior; Bioengineering; BORDERLINE PERSONALITY-DISORDER; Cognition; ELDERLY-PATIENTS; Female; FreeSurfer; FUNCTIONAL-ORGANIZATION; Hippocampal subfields; Hippocampus; Hippocampus - anatomy & histology; HUMAN BRAIN; Humans; Image processing; Image Processing, Computer-Assisted; Image Processing, Computer-Assisted - methods; Image Processing, Computer-Assisted - standards; Imaging; info:eu-repo/classification/ddc/616.8; Life Sciences; Magnetic Resonance Imaging; Magnetic Resonance Imaging - methods; Magnetic Resonance Imaging - standards; Male; MANUAL SEGMENTATION; Medical imaging; Medizin; Memory; MESH: Adult; MESH: Aged; MESH: Amygdala / anatomy & histology; MESH: Female; MESH: Hippocampus / anatomy & histology; MESH: Humans; MESH: Image Processing, Computer-Assisted / methods; MESH: Image Processing, Computer-Assisted / standards; MESH: Magnetic Resonance Imaging / methods; MESH: Magnetic Resonance Imaging / standards; MESH: Male; MESH: Middle Aged; MESH: Neuroimaging / methods; MESH: Neuroimaging / standards; MESH: Reproducibility of Results; MESH: Software; methods [Image Processing, Computer-Assisted]; methods [Magnetic Resonance Imaging]; methods [Neuroimaging]; METHODS FREESURFER; Middle Aged; Multicenter MRI study; Neuroimaging; Neuroimaging - methods; Neuroimaging - standards; Neurosciences. Biological psychiatry. Neuropsychiatry; Nuclei; RC321-571; Regulation; Reliability analysis; Reproducibility of Results; SAMPLE-SIZE CALCULATIONS; Segmentation; Software; standards [Image Processing, Computer-Assisted]; standards [Magnetic Resonance Imaging]; standards [Neuroimaging]; STRUCTURAL DIFFERENCES; Studies; SURFACE-BASED ANALYSIS; Reliability analysis; Hippocampal subfields; FreeSurfer; Amygdalar nuclei; Multicenter MRI study

The amygdala and the hippocampus are two limbic structures that play a critical role in cognition and behavior, however their manual segmentation and that of their smaller nuclei/subfields in multicenter datasets is time consuming and difficult due to the low contrast of standard MRI. Here, we asses...