Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility

• Published in: The Lancet infectious diseases Vol. 14; no. 1; pp. 50 - 56
• Main Authors: Cauchemez, Simon, Fraser, Christophe, Van Kerkhove, Maria D, Donnelly, Christl A, Riley, Steven, Rambaut, Andrew, Enouf, Vincent, van der Werf, Sylvie, Ferguson, Neil M
• Format: Journal Article
• Language: English
• Published: London Elsevier Ltd 01.01.2014; Lancet Publishing Group; Elsevier Limited; Cauchemez et al. Open Access article distributed under the terms of CC BY. Published by Elsevier Ltd
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Basic Reproduction Number; Biological and medical sciences; Child; Child, Preschool; Cluster Analysis; Coronavirus; Coronavirus - classification; Coronavirus - genetics; Coronavirus - isolation & purification; Coronavirus Infections - epidemiology; Coronavirus Infections - transmission; Coronavirus Infections - virology; Epidemics; Epidemiological Monitoring; Female; Human viral diseases; Humans; Infectious Disease; Infectious diseases; Male; Medical research; Medical sciences; Middle Aged; Middle East - epidemiology; Respiratory Tract Infections - epidemiology; Respiratory Tract Infections - transmission; Respiratory Tract Infections - virology; Risk Assessment; Survival Analysis; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Young Adult; Middle East; Infection; Virus; Epidemic; Coronavirus; Surveillance; Respiratory disease; Viral disease; Coronaviridae; Middle East respiratory syndrome; Nidovirales; Quantitative analysis

The novel Middle East respiratory syndrome coronavirus (MERS-CoV) had, as of Aug 8, 2013, caused 111 virologically confirmed or probable human cases of infection worldwide. We analysed epidemiological and genetic data to assess the extent of human infection, the performance of case detection, and th...