Inhibition of Dipeptidyl Peptidase IV Improves Metabolic Control Over a 4-Week Study Period in Type 2 Diabetes

• Published in: Diabetes care Vol. 25; no. 5; pp. 869 - 875
• Main Authors: Ahrén, Bo, Simonsson, Erik, Larsson, Hillevi, Landin-Olsson, Mona, Torgeirsson, Hlin, Jansson, Per-Anders, Sandqvist, Madeléne, Båvenholm, Peter, Efendic, Suad, Eriksson, Jan W., Dickinson, Sheila, Holmes, David
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.05.2002
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Blood Glucose; Clinical Medicine; Diabetes; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - drug therapy; Diabetes. Impaired glucose tolerance; Dipeptidyl Peptidase 4 - drug effects; Double-Blind Method; Drug therapy; Endocrine pancreas. Apud cells (diseases); Endocrinology and Diabetes; Endocrinopathies; Endokrinologi och diabetes; Enzymes; Etiopathogenesis. Screening. Investigations. Target tissue resistance; Female; Glycated Hemoglobin A - analysis; Humans; Insulin - blood; Klinisk medicin; Male; Management. Various non-drug treatments. Langerhans islet grafts; Medical and Health Sciences; Medical sciences; Medicin och hälsovetenskap; Metabolism; Middle Aged; Nitriles - therapeutic use; Peptides; Pyrrolidines - therapeutic use; Time Factors; Treatment Outcome; Type 2 diabetes; United States; Endocrinopathy; Dipeptidyl-peptidase IV; Rat; Enzyme; Rodentia; Glucose; Non insulin dependent diabetes; Insulin; Glucagon like peptide 1; Peptidases; Vertebrata; Mammalia; Animal; Hydrolases; Inhibitor; Combined treatment; Inhibition; Half life

Inhibition of Dipeptidyl Peptidase IV Improves Metabolic Control Over a 4-Week Study Period in Type 2 Diabetes Bo Ahrén , MD, PHD 1 2 , Erik Simonsson , MD 1 , Hillevi Larsson , MD, PHD 1 , Mona Landin-Olsson , MD, PHD 2 , Hlin Torgeirsson , MD 2 , Per-Anders Jansson , MD, PHD 3 , Madeléne Sandqvist...