Altered hypoxia-induced cellular responses and inflammatory profile in lung fibroblasts from COPD patients compared to control subjects - Martin, Ryde; Nora, Marek; Anna, Löfdahl; Olivia, Pekny; Leif, Bjermer; Gunilla, Westergren-Thorsson; Ellen, Tufvesson; Anna-Karin, Larsson-Callerfelt (Respiratory research, 2024)
Keywords: Aged; Analysis; Bronchitis; Case-Control Studies; Cell Hypoxia - physiology; Cells, Cultured; Clinical Medicine; Comparative analysis; Complications and side effects; COPD; Development and progression; Diagnosis; Endoplasmic Reticulum Stress - physiology; Enzyme-linked immunosorbent assay; ER stress; Female; Fibroblasts; Fibroblasts - metabolism; Fibroblasts - pathology; Gene expression; Genes; Genetic aspects; Health aspects; Humans; Hypoxia; Hypoxia - metabolism; Inflammation; Inflammation - metabolism; Inflammation - pathology; Inflammation Mediators - metabolism; Klinisk medicin; Lung - metabolism; Lung - pathology; Lung diseases, Obstructive; Lung fibroblasts; Lungmedicin och allergi; Male; Medical and Health Sciences; Medicin och hälsovetenskap; Middle Aged; Oxidative stress; Oxidative Stress - physiology; Pulmonary Disease, Chronic Obstructive - genetics; Pulmonary Disease, Chronic Obstructive - metabolism; Pulmonary Disease, Chronic Obstructive - pathology; Remodelling; Respiratory Medicine and Allergy; Risk factors; Scientific equipment and supplies industry; Transforming Growth Factor beta1 - metabolism; Transforming growth factors; Vascular endothelial growth factor; Sweden; United States; Germany; Oxidative stress; Remodelling; ER stress; Hypoxia; Inflammation; Lung fibroblasts; Gene expression; COPD