A role for BCL2L13 and autophagy in germline purifying selection of mtDNA - Kremer, Laura S.; Bozhilova, Lyuba V.; Rubalcava-Gracia, Diana; Filograna, Roberta; Upadhyay, Mamta; Koolmeister, Camilla; Chinnery, Patrick F.; Larsson, Nils-Göran (PLoS genetics, 2023)
Keywords: Analysis; Animal models; Animals; Autophagy; Autophagy (Cytology); Autophagy - genetics; Biology and Life Sciences; Cell death; DNA, Mitochondrial - genetics; DNA, Mitochondrial - metabolism; Engineering and Technology; Female; Females; Gene expression; Gene mutations; Genetic aspects; Genetic engineering; Genetic research; Germ Cells - metabolism; Health aspects; Infectious Disease Transmission, Vertical; Kinases; Mammals - genetics; Methods; Mice; Mitochondria; Mitochondria - genetics; Mitochondrial diseases; Mitochondrial DNA; Molecular modelling; Mothers; Mutation; Parkin protein; Prevention; Proteins; Proto-Oncogene Proteins c-bcl-2 - genetics; Proto-Oncogene Proteins c-bcl-2 - metabolism; Recombination; Research and Analysis Methods; Risk factors; Statistical analysis; Stochasticity; Sweden