Community control strategies for scabies: A cluster randomised noninferiority trial

• Published in: PLoS medicine Vol. 18; no. 11; p. e1003849
• Main Authors: Hardy, Myra, Samuela, Josaia, Kama, Mike, Tuicakau, Meciusela, Romani, Lucia, Whitfeld, Margot J, King, Christopher L, Weil, Gary J, Schuster, Tibor, Grobler, Anneke C, Engelman, Daniel, Robinson, Leanne J, Kaldor, John M, Steer, Andrew C
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 10.11.2021; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Aged; Albendazole; Biology and Life Sciences; Child; Child, Preschool; Community health services; Consent; Dosage and administration; Dose-Response Relationship, Drug; Drug dosages; Drug therapy; Earth Sciences; Female; Fiji - epidemiology; Filariasis; Geography; Households; Humans; Impetigo - epidemiology; Infant; Infection control; Islands; Ivermectin; Ivermectin - administration & dosage; Ivermectin - therapeutic use; Male; Medicine and Health Sciences; Methods; Middle Aged; Monte Carlo simulation; Parasitic diseases; Permethrin; Residence Characteristics; Risk Factors; Scabies; Scabies - drug therapy; Scabies - epidemiology; Scabies - prevention & control; Skin; Tropical diseases; Young Adult; Fiji; Rotuma

Scabies is a neglected tropical disease hyperendemic to many low- and middle-income countries. Scabies can be successfully controlled using mass drug administration (MDA) using 2 doses of ivermectin-based treatment. If effective, a strategy of 1-dose ivermectin-based MDA would have substantial advan...