Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution - Uchi, Ryutaro; Takahashi, Yusuke; Niida, Atsushi; Shimamura, Teppei; Hirata, Hidenari; Sugimachi, Keishi; Sawada, Genta; Iwaya, Takeshi; Kurashige, Junji; Shinden, Yoshiaki; Iguchi, Tomohiro; Eguchi, Hidetoshi; et al. (PLoS genetics, 2016)
Keywords: Aged; Aged, 80 and over; Aging - genetics; Biological Evolution; Biology and life sciences; Cancer metastasis; Class I Phosphatidylinositol 3-Kinases; Colorectal cancer; Colorectal Neoplasms - genetics; Colorectal Neoplasms - pathology; CpG Islands; DNA Methylation; Epigenesis, Genetic; Evolutionary adaptation; Exome; Female; Founder Effect; Gene mutation; Genetic aspects; Health aspects; Humans; Male; Medical research; Medicine and Health Sciences; Middle Aged; Models, Biological; Mutation; Phosphatidylinositol 3-Kinases - genetics; Polymorphism, Single Nucleotide; Research and Analysis Methods; Studies