Dissecting Inflammatory Complications in Critically Injured Patients by Within-Patient Gene Expression Changes: A Longitudinal Clinical Genomics Study - Desai, Keyur H.; Tan, Chuen Seng; Leek, Jeffrey T.; Maier, Ronald V.; Tompkins, Ronald G.; Storey, John D. (PLoS medicine, 2011)
Keywords: Adolescent; Adult; Antigen Presentation; Biology; Care and treatment; Female; Gene expression; Gene Expression Regulation; Genes, MHC Class II; Genomics; Humans; Immune system; Inflammation; Inflammation - complications; Inflammation - immunology; Leukocytes - cytology; Leukocytes - immunology; Longitudinal Studies; Male; MAP Kinase Signaling System; Mathematics; Medicine; Middle Aged; Multiple Organ Failure - etiology; Multiple Organ Failure - immunology; Multiple Organ Failure - physiopathology; Oligonucleotide Array Sequence Analysis; Principal components analysis; Prognosis; Prospective Studies; Statistical analysis; Statistical methods; Studies; Trauma; Wounds and injuries; Wounds and Injuries - complications; Wounds and Injuries - genetics; Wounds and Injuries - immunology; Wounds and Injuries - physiopathology; Young Adult; United States; United States--US; Genes, MHC Class II; Prospective Studies; Oligonucleotide Array Sequence Analysis; Humans; Middle Aged; Gene Expression Regulation; Male; Inflammation; Leukocytes; MAP Kinase Signaling System; Multiple Organ Failure; Wounds & Injuries; Young Adult; Antigen Presentation; Adolescent; Adult; Female; Longitudinal Studies