NMR Metabolomic Analysis of Fecal Water from Subjects on a Vegetarian Diet

• Published in: Biological & Pharmaceutical Bulletin Vol. 31; no. 6; pp. 1192 - 1198
• Main Authors: Rafter, Joseph James, Verpoorte, Robert, Karlsson, Pernilla Christina, Pettersson, Jenny, Choi, Young Hae, Bohlin, Lars
• Format: Journal Article
• Language: English
• Published: Japan The Pharmaceutical Society of Japan 01.06.2008; Pharmaceutical Society of Japan; Japan Science and Technology Agency
• Subjects: Anti-Inflammatory Agents, Non-Steroidal - pharmacology; colon cancer; Cyclooxygenase 2 Inhibitors - metabolism; Cyclooxygenase 2 Inhibitors - pharmacology; cyclooxygenase-2 inhibitor; Diet, Vegetarian; Dinoprostone - analysis; Dinoprostone - metabolism; Fatty Acids - metabolism; Feces - chemistry; HT29 Cells; Humans; Magnetic Resonance Spectroscopy; MEDICIN; MEDICINE; Metabolism; metabolomic; nuclear magnetic resonance; Passive Cutaneous Anaphylaxis; Tissue Extracts - metabolism; Tissue Extracts - pharmacology; vegetarian fecal water; Water - chemistry; Water - metabolism; nuclear magnetic resonance; cyclooxygenase-2 inhibitor

A vegetarian diet rich in phytochemicals may prevent colon carcinogenesis by affecting biochemical processes in the colonic mucosa. Compounds passing the digestive system reaching the colon could potentially be detected in fecal water. We previously reported that intact fecal water samples from huma...