Isolation of a Novel Swine Influenza Virus from Oklahoma in 2011 Which Is Distantly Related to Human Influenza C Viruses

• Published in: PLoS pathogens Vol. 9; no. 2; p. e1003176
• Main Authors: Hause, Ben M., Ducatez, Mariette, Collin, Emily A., Ran, Zhiguang, Liu, Runxia, Sheng, Zizhang, Armien, Anibal, Kaplan, Bryan, Chakravarty, Suvobrata, Hoppe, Adam D., Webby, Richard J., Simonson, Randy R., Li, Feng
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.02.2013; Public Library of Science (PLoS)
• Subjects: Amino acids; Animal biology; Animals; Antibodies, Viral - blood; Antigens, Viral - immunology; Base Sequence; Binding sites; Biology; Cell culture; Cell Culture Techniques; Comparative analysis; Evolution; Experiments; Ferrets; Gammainfluenzavirus - genetics; Gammainfluenzavirus - immunology; Gammainfluenzavirus - isolation & purification; Gammainfluenzavirus - ultrastructure; Genome, Viral - genetics; Health aspects; Hemagglutination Inhibition Tests; Hemagglutinins, Viral - genetics; Hemagglutinins, Viral - metabolism; Hogs; Host Specificity; Host-parasite relationships; Human health and pathology; Humans; Influenza; Life Sciences; Male; Microbiology and Parasitology; Models, Molecular; Molecular Sequence Data; Oklahoma; Orthomyxoviridae Infections - immunology; Orthomyxoviridae Infections - transmission; Orthomyxoviridae Infections - virology; Pandemics; Phylogeny; Physiological aspects; Proteins; Santé publique et épidémiologie; Sequence Analysis, DNA; Structural analysis; Swine; Swine Diseases - immunology; Swine Diseases - transmission; Swine Diseases - virology; Viral Fusion Proteins - genetics; Viral Fusion Proteins - metabolism; Viruses; Oklahoma; United States; Genome, Viral; Humans; Oklahoma; Models, Molecular; Molecular Sequence Data; Host Specificity; Male; Swine Diseases; Phylogeny; Antibodies, Viral; Ferrets; Sequence Analysis, DNA; Hemagglutination Inhibition Tests; Influenzavirus C; Animals; Antigens, Viral; Swine; Base Sequence; Hemagglutinins, Viral; Orthomyxoviridae Infections; Cell Culture Techniques; Viral Fusion Proteins

Of the Orthomyxoviridae family of viruses, only influenza A viruses are thought to exist as multiple subtypes and has non-human maintenance hosts. In April 2011, nasal swabs were collected for virus isolation from pigs exhibiting influenza-like illness. Subsequent electron microscopic, biochemical,...