Representation of abstract semantic knowledge in populations of human single neurons in the medial temporal lobe

• Published in: PLoS biology Vol. 17; no. 6; p. e3000290
• Main Authors: Reber, Thomas P., Bausch, Marcel, Mackay, Sina, Boström, Jan, Elger, Christian E., Mormann, Florian
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 03.06.2019; Public Library of Science (PLoS)
• Subjects: Activity patterns; Adult; Amygdala; Biology and Life Sciences; Brain; Brain Mapping - methods; Categories; Classifiers; Epilepsy - physiopathology; Female; Firing pattern; Humans; Knowledge; Knowledge representation; Magnetic Resonance Imaging - methods; Male; Medicine and Health Sciences; Memory; Memory - physiology; Middle Aged; Neocortex; Neocortex - physiology; Neural circuitry; Neurons; Neurons - physiology; NMR; Nuclear magnetic resonance; Photic Stimulation - methods; Physiological aspects; Semantics; Single-Cell Analysis - methods; Social Sciences; Software; Studies; Temporal lobe; Temporal Lobe - diagnostic imaging; Temporal Lobe - physiology; Trends; Unit activity; Germany

Sensory experience elicits complex activity patterns throughout the neocortex. Projections from the neocortex converge onto the medial temporal lobe (MTL), in which distributed neocortical firing patterns are distilled into sparse representations. The precise nature of these neuronal representations...