68 Ga‐labeled Ciprofloxacin Conjugates as Radiotracers for Targeting Bacterial Infection

• Published in: Chemical biology & drug design Vol. 87; no. 5; pp. 680 - 686
• Main Authors: Satpati, Drishty, Arjun, Chanda, Krishnamohan, Repaka, Samuel, Grace, Banerjee, Sharmila
• Format: Journal Article
• Language: English
• Published: 01.05.2016

With an aim of developing a bacteria‐specific molecular imaging agent, ciprofloxacin has been modified with a propylamine spacer and linked to two common bifunctional chelators, p‐ SCN ‐Bz‐ DOTA and p‐ SCN ‐Bz‐ NOTA . The two ciprofloxacin conjugates, CP ‐ PA ‐ SCN ‐Bz‐ DOTA ( 1 ) and CP ‐ PA ‐ SCN...