Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection - Henn, Matthew R.; Boutwell, Christian L.; Charlebois, Patrick; Lennon, Niall J.; Power, Karen A.; Macalalad, Alexander R.; Berlin, Aaron M.; Malboeuf, Christine M.; Ryan, Elizabeth M.; Gnerre, Sante; Zody, Michael C.; Erlich, Rachel L.; et al. (PLoS pathogens, 2012)
Keywords: Adaptations; Algorithms; Biology; CD8 antigen; CD8-Positive T-Lymphocytes - immunology; Data processing; DNA sequencing; Epitopes; Evolution; Genetic aspects; Genetic Variation; Genome, Viral - genetics; Genome-Wide Association Study; Genomes; Genomic Structural Variation; Genomics; Health aspects; Histocompatibility antigen HLA; HIV (Viruses); HIV Infections - immunology; HIV Infections - prevention & control; HIV Infections - virology; HIV-1 - genetics; HIV-1 - immunology; HIV-1 - pathogenicity; Human immunodeficiency virus 1; Humans; Immune Evasion - genetics; Immune Evasion - immunology; Immune response; Immune system; Immunity; Immunology; Infection; Infections; Lymphocytes T; Medicine; Mutation; Nucleotide sequencing; Oligonucleotide Array Sequence Analysis; Pathogens; Physiological aspects; Replication; Reversion; RNA, Viral - analysis; Sequence Analysis, RNA; Vaccines; Viral genetics; Viral Vaccines - immunology; Viremia; United States; HIV Infections; HIV-1; Genome, Viral; Genome-Wide Association Study; Oligonucleotide Array Sequence Analysis; Humans; CD8-Positive T-Lymphocytes; Genetic Variation; Genomic Structural Variation; Immune Evasion; Sequence Analysis, RNA; RNA, Viral; Viral Vaccines