Aging and the relationships between long-axis systolic and early diastolic excursion, isovolumic relaxation time and left ventricular length—Implications for the interpretation of aging effects on e

• Published in: PloS one Vol. 14; no. 1; p. e0210277
• Main Author: Peverill, Roger E.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 07.01.2019; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Age; Aged; Aging; Aging (Biology); Aging - physiology; Biology and Life Sciences; Blood Flow Velocity; Blood pressure; Body mass index; Body size; Consent; Contraction; Correlation analysis; Diabetes; Diastole; Echocardiography, Doppler, Pulsed; Female; Health aspects; Heart; Heart Ventricles - physiopathology; Humans; Hypertension; Male; Medicine and Health Sciences; Middle Aged; Multivariate analysis; People and Places; Physical Sciences; Prolongation; Prospective Studies; Relaxation time; Studies; Systole; Velocity; Ventricle; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left - physiology; Young Adult

Both the left ventricular (LV) long-axis peak early diastolic lengthening velocity (e`) and long-axis early diastolic excursion (EDExc) decrease with age, but the mechanisms underlying these decreases are not fully understood. The aim of this study was to investigate the relative contributions to ag...