The relationship between thyroid function and cerebral blood flow in mild cognitive impairment and Alzheimer’s disease

• Published in: PloS one Vol. 14; no. 4; p. e0214676
• Main Authors: Nomoto, Shohei, Kinno, Ryuta, Ochiai, Hirotaka, Kubota, Satomi, Mori, Yukiko, Futamura, Akinori, Sugimoto, Azusa, Kuroda, Takeshi, Yano, Satoshi, Murakami, Hidetomo, Shirasawa, Takako, Yoshimoto, Takahiko, Minoura, Akira, Kokaze, Akatsuki, Ono, Kenjiro
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 03.04.2019; Public Library of Science (PLoS)
• Subjects: Age; Aged; Aged, 80 and over; Aging; Alzheimer Disease - physiopathology; Alzheimer's disease; Biology and Life Sciences; Blood; Blood flow; Brain; CAT scans; Cerebral blood flow; Cerebral circulation; Cerebrovascular Circulation; Cognition & reasoning; Cognitive ability; Cognitive disorders; Cognitive Dysfunction - physiopathology; Computation; Computed tomography; Dementia; Diagnosis; Diagnostic imaging; Disease prevention; Emission analysis; Emissions; Female; Glycoproteins; Health aspects; Health care; Hippocampus; Hormones; Humans; Hygiene; Hypothyroidism; Impairment; Linear Models; Male; Medical research; Medical schools; Medicine and Health Sciences; Memory; Metabolism; Middle Aged; Multiple regression analysis; Neurology; NMR; Nuclear magnetic resonance; Patients; Perfusion; Photon emission; Pituitary hormones; Preventive medicine; Public health; Regression analysis; Research and Analysis Methods; Single photon emission computed tomography; Studies; Systematic review; Thyroid; Thyroid Function Tests; Thyroid gland; Thyroid Gland - physiopathology; Thyroid hormones; Thyroid Hormones - blood; Tomography; Triiodothyronine; Japan

The thyroid hormones have been reported to be associated with cognitive decline and Alzheimer's disease. The relationship between thyroid function within the normal range and cerebral blood flow in Alzheimer's disease patients has been shown in a recent study. Mild cognitive impairment is...