High-resolution harmonics ultrasound imaging for non-invasive characterization of wound healing in a pre-clinical swine model

• Published in: PloS one Vol. 10; no. 3; p. e0122327
• Main Authors: Gnyawali, Surya C, Barki, Kasturi G, Mathew-Steiner, Shomita S, Dixith, Sriteja, Vanzant, Daniel, Kim, Jayne, Dickerson, Jennifer L, Datta, Soma, Powell, Heather, Roy, Sashwati, Bergdall, Valerie, Sen, Chandan K
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 23.03.2015; Public Library of Science (PLoS)
• Subjects: Angiogenesis; Animals; Biomarkers; Biomedical engineering; Biopsy; Blood; Blood flow; Chemical properties; Diagnostic Imaging - methods; Digital imaging; Doppler effect; Elasticity Imaging Techniques; Extracellular matrix; Gene expression; Gene therapy; Heart; High resolution; Image resolution; Imaging systems; Lasers; Livestock; Medicine; Models, Animal; Molecular modelling; Noise; Pressure; Regional Blood Flow; Skin; Stiffness; Studies; Swine; Ultrasonic imaging; Ultrasonography - methods; Ultrasound; Ultrasound imaging; Wound Healing; United States > US; Ohio

This work represents the first study employing non-invasive high-resolution harmonic ultrasound imaging to longitudinally characterize skin wound healing. Burn wounds (day 0-42), on the dorsum of a domestic Yorkshire white pig were studied non-invasively using tandem digital planimetry, laser speckl...