Determinants of Medication Adherence to Antihypertensive Medications among a Chinese Population Using Morisky Medication Adherence Scale

Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among...

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Published inPloS one Vol. 8; no. 4; p. e62775
Main Authors Lee, Gabrielle K. Y., Wang, Harry H. X., Liu, Kirin Q. L., Cheung, Yu, Morisky, Donald E., Wong, Martin C. S.
Format Journal Article
LanguageEnglish
Published United States Public Library of Science 25.04.2013
Public Library of Science (PLoS)
Subjects
Adhesion
Aged
Analysis
Antihypertensive agents
Antihypertensive Agents - therapeutic use
Antihypertensive drugs
Antihypertensives
Asian People
Biology
Blood pressure
Clinics
Demographics
Drug therapy
Drugs
Female
Health care policy
Health risk assessment
Humans
Hypertension
Hypertension - drug therapy
Male
Medical research
Medication adherence
Medication Adherence - statistics & numerical data
Medicine
Medicine, Experimental
Middle Aged
Patient compliance
Patients
Public health
Regression analysis
Studies
China
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Abstract Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients. A cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points). From 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence. This study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
AbstractList Background and objectivesPoor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients.MethodsA cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points).ResultsFrom 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence.ConclusionThis study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients.BACKGROUND AND OBJECTIVESPoor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients.A cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points).METHODSA cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points).From 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence.RESULTSFrom 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence.This study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.CONCLUSIONThis study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients. A cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points). From 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence. This study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
Background and Objectives Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients. Methods A cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points). Results From 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence. Conclusion This study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients. A cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points). From 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence. This study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
Background and Objectives Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure, mostly caused by poor drug adherence. However, there are relatively few reports studying the adherence levels and their associated factors among Chinese patients. This study aimed to study the adherence profiles and the factors associated with antihypertensive drug adherence among Chinese patients. Methods A cross-sectional study was conducted in an outpatient clinic located in the New Territories Region of Hong Kong. Adult patients who were currently taking at least one antihypertensive drug were invited to complete a self-administered questionnaire, consisting of basic socio-demographic profile, self-perceived health status, and self-reported medication adherence. The outcome measure was the Morisky Medication Adherence Scale (MMAS-8). Good adherence was defined as MMAS scores greater than 6 points (out of a total score of 8 points). Results From 1114 patients, 725 (65.1%) had good adherence to antihypertensive agents. Binary logistic regression analysis was conducted. Younger age, shorter duration of antihypertensive agents used, job status being employed, and poor or very poor self-perceived health status were negatively associated with drug adherence. Conclusion This study reported a high proportion of poor medication adherence among hypertensive subjects. Patients with factors associated with poor adherence should be more closely monitored to optimize their drug taking behavior.
Audience Academic
Author Liu, Kirin Q. L.
Lee, Gabrielle K. Y.
Wang, Harry H. X.
Cheung, Yu
Wong, Martin C. S.
Morisky, Donald E.
AuthorAffiliation University of Ottawa, Canada
2 New Territories East Cluster, Hospital Authority, Hong Kong SAR, China
3 Department of Community Health Sciences, UCLA Fielding School of Public Health, United States of America
1 School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China
AuthorAffiliation_xml – name: 1 School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China
– name: 2 New Territories East Cluster, Hospital Authority, Hong Kong SAR, China
– name: 3 Department of Community Health Sciences, UCLA Fielding School of Public Health, United States of America
– name: University of Ottawa, Canada
Author_xml – sequence: 1
  givenname: Gabrielle K. Y.
  surname: Lee
  fullname: Lee, Gabrielle K. Y.
– sequence: 2
  givenname: Harry H. X.
  surname: Wang
  fullname: Wang, Harry H. X.
– sequence: 3
  givenname: Kirin Q. L.
  surname: Liu
  fullname: Liu, Kirin Q. L.
– sequence: 4
  givenname: Yu
  surname: Cheung
  fullname: Cheung, Yu
– sequence: 5
  givenname: Donald E.
  surname: Morisky
  fullname: Morisky, Donald E.
– sequence: 6
  givenname: Martin C. S.
  surname: Wong
  fullname: Wong, Martin C. S.
BackLink https://www.ncbi.nlm.nih.gov/pubmed/23638143$$D View this record in MEDLINE/PubMed
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Conceived and designed the experiments: MCSW. Performed the experiments: MCSW GKYL HHXW KQLL. Analyzed the data: MCSW GKYL HHXW KQLL DEM. Contributed reagents/materials/analysis tools: YC DEM. Wrote the paper: MCSW GKYL DEM.
Competing Interests: The authors have declared that no competing interests exist.
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Snippet Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful control of blood pressure,...
Background and Objectives Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful...
Background and objectivesPoor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful...
Background and Objectives Poor adherence to medications is one of the major public health challenges. Only one-third of the population reported successful...
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StartPage e62775
SubjectTerms Adhesion
Aged
Analysis
Antihypertensive agents
Antihypertensive Agents - therapeutic use
Antihypertensive drugs
Antihypertensives
Asian People
Biology
Blood pressure
Clinics
Demographics
Drug therapy
Drugs
Female
Health care policy
Health risk assessment
Humans
Hypertension
Hypertension - drug therapy
Male
Medical research
Medication adherence
Medication Adherence - statistics & numerical data
Medicine
Medicine, Experimental
Middle Aged
Patient compliance
Patients
Public health
Regression analysis
Studies
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Title Determinants of Medication Adherence to Antihypertensive Medications among a Chinese Population Using Morisky Medication Adherence Scale
URI https://www.ncbi.nlm.nih.gov/pubmed/23638143
https://www.proquest.com/docview/1346593004
https://www.proquest.com/docview/1348499827
https://pubmed.ncbi.nlm.nih.gov/PMC3636185
https://doaj.org/article/2add7ea7dc5f44688c88340d208ba796
http://dx.doi.org/10.1371/journal.pone.0062775
Volume 8
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