Evaluation of Toxicity and Biodegradability of Cholinium Amino Acids Ionic Liquids

• Published in: PloS one Vol. 8; no. 3; p. e59145
• Main Authors: Hou, Xue-Dan, Liu, Qiu-Ping, Smith, Thomas J., Li, Ning, Zong, Min-Hua
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 15.03.2013; Public Library of Science (PLoS)
• Subjects: Acetylcholinesterase; Acetylcholinesterase - metabolism; Amino acids; Amino Acids - chemical synthesis; Amino Acids - metabolism; Amino Acids - pharmacology; Analysis; Animals; Bacteria; Biocompatibility; Biodegradability; Biodegradation; Biodegradation, Environmental; Bioengineering; Biological products; Biology; Biomass; Biomaterials; Biomedical materials; Carbon dioxide; Cellulase; Chemistry; Cholinesterase Inhibitors - chemical synthesis; Cholinesterase Inhibitors - metabolism; Cholinesterase Inhibitors - pharmacology; Electrophorus; Engineering; Enzymes; Fish Proteins - antagonists & inhibitors; Fish Proteins - metabolism; Gram-Negative Bacteria - drug effects; Gram-Negative Bacteria - growth & development; Gram-Positive Bacteria - drug effects; Gram-Positive Bacteria - growth & development; Headspace; Imidazoles - metabolism; Imidazoles - pharmacology; Ionic liquids; Ionic Liquids - chemical synthesis; Ionic Liquids - metabolism; Ionic Liquids - pharmacology; Ions; Laboratories; Lignin; Microorganisms; Mineralization; Pretreatment; Solvents; Structure-Activity Relationship; Toxicity; Toxicity testing; Wastewater; China

Cholinium amino acid ionic liquids ([Ch][AA] ILs), which are wholly composed of renewable biomaterials, have recently been demonstrated to have very promising properties for applications in organic synthesis and biomass pretreatment. In this work, the toxicity of these ILs toward enzymes and bacteri...