Green Tea Phenolic Epicatechins Inhibit Hepatitis C Virus Replication via Cycloxygenase-2 and Attenuate Virus-Induced Inflammation - Lin, Ying-Ting; Wu, Yu-Hsuan; Tseng, Chin-Kai; Lin, Chun-Kuang; Chen, Wei-Chun; Hsu, Yao-Chin; Lee, Jin-Ching (PloS one, 2013)
Keywords: Amino acids; Anemia; Antibiotics; Antiviral Agents - pharmacology; Biology; Biotechnology; Cancer therapies; Carcinoma, Hepatocellular - drug therapy; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - pathology; Carcinoma, Hepatocellular - virology; Catechin; Catechin - pharmacology; Cats; Cell Line, Tumor; Cellular signal transduction; Chronic infection; Cyclooxygenase 2 - genetics; Cyclooxygenase 2 - metabolism; Cyclooxygenase-2; Cyclooxygenases; Deoxycytidine - analogs & derivatives; Deoxycytidine - pharmacology; Enzyme inhibitors; Epicatechin; Gene expression; Gene Expression - drug effects; Genetic aspects; Green tea; Health aspects; Health risks; Hepacivirus - drug effects; Hepacivirus - physiology; Hepatitis; Hepatitis C; Hepatitis C virus; Hepatitis C, Chronic - drug therapy; Hepatitis C, Chronic - genetics; Hepatitis C, Chronic - pathology; Hepatitis C, Chronic - virology; Hepatocellular carcinoma; Hepatoma; Humans; IL-1β; Infections; Inflammation; Inflammation - prevention & control; Inhibition; Interferon; Interferon-alpha - pharmacology; Interleukin; Interleukin-1beta - antagonists & inhibitors; Interleukin-1beta - genetics; Interleukins; Isomers; Life sciences; Liver; Liver diseases; Medicine; Natural products; Nitric Oxide Synthase Type II - antagonists & inhibitors; Nitric Oxide Synthase Type II - genetics; Oligopeptides - pharmacology; Phenolic compounds; Phenols; Product development; Prostate; Proteins; Replication; Risk factors; RNA polymerase; RNA, Viral - antagonists & inhibitors; Stereoisomerism; Tea; Tea - chemistry; Tumor Necrosis Factor-alpha - antagonists & inhibitors; Tumor Necrosis Factor-alpha - genetics; Tumor necrosis factor-α; Viral infections; Virus replication; Virus Replication - drug effects; Viruses; United States--US; Taiwan