Identification and Characterization of Sebaceous Gland Atrophy-Sparing DGAT1 Inhibitors - Muise, Eric S.; Zhu, Yonghua; Verras, Andreas; Karanam, Bindhu V.; Gorski, Judith; Weingarth, Drew; Lin, Hua V.; Hwa, Joyce; Thompson, John R.; Hu, Guanghui; Liu, Jian; He, Shuwen; et al. (PloS one, 2014)
Keywords: Animals; Atrophy; Atrophy - chemically induced; Atrophy - enzymology; Biology; Biomarkers; Biomarkers - metabolism; Biosynthesis; Chemistry; Diabetes; Diacylglycerol; Diacylglycerol O-acyltransferase; Diacylglycerol O-Acyltransferase - antagonists & inhibitors; Diglycerides; Drug Discovery; Enzyme Inhibitors - adverse effects; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - metabolism; Enzyme Inhibitors - pharmacology; Hydrophobic and Hydrophilic Interactions; Inhibition; Inhibitors; Laboratories; Lipids; Male; Medicine; Metabolic disorders; Metabolic pathways; Metabolism; Mice; Obesity; Peptides; Pharmaceutical industry; Pharmacology; Physical properties; R&D; Research & development; Ribonucleic acid; RNA; Rodents; Sebaceous gland; Sebaceous Glands - drug effects; Sebaceous Glands - pathology; Skin; Skin - drug effects; Skin - enzymology; Skin - metabolism; Small Molecule Libraries - adverse effects; Small Molecule Libraries - chemistry; Small Molecule Libraries - metabolism; Small Molecule Libraries - pharmacology; Tissues; Vaccines; United States--US; New Jersey