Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor

A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNA and complementary DNA encoding this subunit (alpha2) were cloned and analyzed. Complementary DNA expression studies in Xenopus oocytes revealed that the injection of messe...

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Published inScience (American Association for the Advancement of Science) Vol. 240; no. 4850; pp. 330 - 334
Main Authors Wada, Keiji, Ballivet, Marc, Boulter, Jim, Connolly, John, Wada, Etsuko, Deneris, Evan S., Swanson, Larry W., Heinemann, Steve, Patrick, Jim
Format Journal Article
LanguageEnglish
Published Washington, DC The American Association for the Advancement of Science 15.04.1988
American Association for the Advancement of Science
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Abstract A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNA and complementary DNA encoding this subunit (alpha2) were cloned and analyzed. Complementary DNA expression studies in Xenopus oocytes revealed that the injection of messenger RNAs (mRNAs) for alpha2 and beta2 (a neuronal nAChR subunit) led to the generation of a functional nAChR. In contrast to the other known neuronal nAChRs, the receptor produced by the injection of alpha2 and beta2 mRNAs was resistant to the α-neurotoxin Bgt3.1. In situ hybridization histochemistry showed that alpha2 mRNA was expressed in a small number of regions, in contrast to the wide distribution of the other known agonist-binding subunits (alpha3 and alpha4) mRNAs. These results demonstrate that the alpha2 subunit differs from other known agonist-binding α-subunits of nAChRs in its distribution in the brain and in its pharmacology.
AbstractList A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Experimental results demonstrate that the alpha2 subunit differs from other known agonist-binding subunits.
A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNA and complementary DNA encoding this subunit (alpha 2) were cloned and analyzed. Complementary DNA expression studies in Xenopus oocytes revealed that the injection of messenger RNAs (mRNAs) for alpha 2 and beta 2 (a neuronal nAChR subunit) led to the generation of a functional nAChR. In contrast to the other known neuronal nAChRs, the receptor produced by the injection of alpha 2 and beta 2 mRNAs was resistant to the alpha-neurotoxin Bgt3.1. In situ hybridization histochemistry showed that alpha 2 mRNA was expressed in a small number of regions, in contrast to the wide distribution of the other known agonist-binding subunits (alpha 3 and alpha 4) mRNAs. These results demonstrate that the alpha 2 subunit differs from other known agonist-binding alpha-subunits of nAChRs in its distribution in the brain and in its pharmacology.
A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNa and complementary DNA encoding this subunit (alpha2) were cloned and analyzed. The results demonstrate that the alpha2 subunit differs from other known agonist-binding alpha -subunits of nAChRs in its distribution in the brain and in its pharmacology.
A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNA and complementary DNA encoding this subunit (alpha2) were cloned and analyzed. Complementary DNA expression studies in Xenopus oocytes revealed that the injection of messenger RNAs (mRNAs) for alpha2 and beta2 (a neuronal nAChR subunit) led to the generation of a functional nAChR. In contrast to the other known neuronal nAChRs, the receptor produced by the injection of alpha2 and beta2 mRNAs was resistant to the α-neurotoxin Bgt3.1. In situ hybridization histochemistry showed that alpha2 mRNA was expressed in a small number of regions, in contrast to the wide distribution of the other known agonist-binding subunits (alpha3 and alpha4) mRNAs. These results demonstrate that the alpha2 subunit differs from other known agonist-binding α-subunits of nAChRs in its distribution in the brain and in its pharmacology.
A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNA and complementary DNA encoding this subunit (alpha2) were cloned and analyzed. Complementary DNA expression studies in Xenopus oocytes revealed that the injection of messenger RNAs (mRNAs) for alpha2 and beta2 (a neuronal nAChR subunit) led to the generation of a functional nAChR. In contrast to the other known neuronal nAChRs, the receptor produced by the injection of alpha2 and beta2 mRNAs was resistant to the α-neurotoxin Bgt3.1. In situ hybridization histochemistry showed that alpha2 mRNA was expressed in a small number of regions, in contrast to the wide distribution of the other known agonist-binding subunits (alpha3 and alpha4) mRNAs. These results demonstrate that the alpha2 subunit differs from other known agonist-binding α-subunits of nAChRs in its distribution in the brain and in its pharmacology.
Audience Academic
Author Wada, Keiji
Ballivet, Marc
Deneris, Evan S.
Wada, Etsuko
Swanson, Larry W.
Boulter, Jim
Patrick, Jim
Heinemann, Steve
Connolly, John
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  fullname: Wada, Etsuko
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  givenname: Evan S.
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Cites_doi 10.1038/319368a0
10.1093/nar/14.21.8427
10.1073/pnas.74.12.5463
10.1073/pnas.84.21.7763
10.1038/328215a0
10.1038/328221a0
10.1016/0896-6273(88)90208-5
10.1002/j.1460-2075.1986.tb04389.x
10.1073/pnas.74.2.560
10.1093/nar/12.2.857
10.1146/annurev.cb.01.110185.001533
10.1016/0014-5793(87)80272-7
10.1016/S0006-3495(84)84152-1
10.1038/321406a0
10.1038/307604a0
10.1523/JNEUROSCI.07-06-01792.1987
10.1038/327515a0
10.1038/324670a0
10.1021/bi00383a003
10.1016/0092-8674(87)90705-7
10.1038/315761a0
10.1523/JNEUROSCI.05-09-02545.1985
10.1093/nar/14.11.4683
10.1016/0014-5793(86)80881-X
10.1016/S0021-9258(19)75267-3
10.1016/S0021-9258(20)71257-3
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Issue 4850
Keywords Brain
Molecular hybridization
In vitro translation
Rat
In situ
Rodentia
Central nervous system
Gene expression
Vertebrata
Cholinergic receptor
Mammalia
Microinjection
Molecular cloning
Nicotinic receptor
Aminoacid sequence
Language English
License CC BY 4.0
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References (e_1_2_1_19_1) 1986; 205
(e_1_2_1_17_1) 1986; 5
(e_1_2_1_33_1) 1986; 6
(e_1_2_1_3_1) 1985; 5
(e_1_2_1_35_1) 1985; 315
(e_1_2_1_30_1) 1979; 76
(e_1_2_1_39_1) 1987; 327
(e_1_2_1_16_1) 1986
(e_1_2_1_34_1) 1985; 1
(e_1_2_1_10_1) 1984; 81
(e_1_2_1_12_1) 1987; 48
(e_1_2_1_26_1) 1984; 307
(e_1_2_1_18_1) 1987; 7
e_1_2_1_24_1
(e_1_2_1_11_1) 1987; 26
e_1_2_1_22_1
(e_1_2_1_20_1) 1986; 324
(e_1_2_1_4_1) 1986; 319
(e_1_2_1_2_1) 1986; 14
(e_1_2_1_28_1) 1986
(e_1_2_1_23_1) 1974; 40
(e_1_2_1_14_1) 1987; 328
(e_1_2_1_25_1) 1977; 74
(e_1_2_1_9_1) 1988; 1
(e_1_2_1_38_1) 1987; 219
(e_1_2_1_21_1) 1984; 259
e_1_2_1_31_1
e_1_2_1_5_1
(e_1_2_1_6_1) 1986; 83
e_1_2_1_1_1
(e_1_2_1_13_1) 1986; 83
(e_1_2_1_15_1) 1984; 45
(e_1_2_1_32_1) 1987; 328
(e_1_2_1_7_1) 1978; 75
e_1_2_1_37_1
(e_1_2_1_29_1) 1977; 252
e_1_2_1_36_1
(e_1_2_1_8_1) 1978; 75
(e_1_2_1_27_1) 1986; 321
References_xml – volume: 83
  start-page: 917
  year: 1986
  ident: e_1_2_1_6_1
  publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
– volume: 319
  start-page: 368
  year: 1986
  ident: e_1_2_1_4_1
  publication-title: NATURE
  doi: 10.1038/319368a0
– volume: 14
  start-page: 8427
  year: 1986
  ident: e_1_2_1_2_1
  publication-title: NUCLEIC ACIDS RESEARCH
  doi: 10.1093/nar/14.21.8427
– ident: e_1_2_1_31_1
  doi: 10.1073/pnas.74.12.5463
– ident: e_1_2_1_5_1
  doi: 10.1073/pnas.84.21.7763
– volume: 328
  start-page: 215
  year: 1987
  ident: e_1_2_1_14_1
  publication-title: NATURE
  doi: 10.1038/328215a0
– volume: 328
  start-page: 221
  year: 1987
  ident: e_1_2_1_32_1
  publication-title: NATURE
  doi: 10.1038/328221a0
– volume: 1
  start-page: 45
  year: 1988
  ident: e_1_2_1_9_1
  publication-title: Neuron
  doi: 10.1016/0896-6273(88)90208-5
– start-page: 359
  year: 1986
  ident: e_1_2_1_16_1
  publication-title: Nicotinic Acetylcholine Receptor: Structure and Function
– volume: 6
  start-page: 4067
  year: 1986
  ident: e_1_2_1_33_1
  publication-title: MOLECULAR AND CELLULAR BIOLOGY
– volume: 5
  start-page: 1503
  year: 1986
  ident: e_1_2_1_17_1
  publication-title: EMBO JOURNAL
  doi: 10.1002/j.1460-2075.1986.tb04389.x
– ident: e_1_2_1_37_1
– volume: 83
  start-page: 4076
  year: 1986
  ident: e_1_2_1_13_1
  publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
– ident: e_1_2_1_24_1
  doi: 10.1073/pnas.74.2.560
– ident: e_1_2_1_1_1
– ident: e_1_2_1_22_1
  doi: 10.1093/nar/12.2.857
– volume: 1
  start-page: 317
  year: 1985
  ident: e_1_2_1_34_1
  publication-title: ANNUAL REVIEW OF CELL BIOLOGY
  doi: 10.1146/annurev.cb.01.110185.001533
– volume: 219
  start-page: 459
  year: 1987
  ident: e_1_2_1_38_1
  publication-title: FEBS LETTERS
  doi: 10.1016/0014-5793(87)80272-7
– volume: 40
  start-page: 17
  year: 1974
  ident: e_1_2_1_23_1
  publication-title: BIOCHEMICAL SOCIETY SYMPOSIA
– volume: 45
  start-page: 249
  year: 1984
  ident: e_1_2_1_15_1
  publication-title: BIOPHYSICAL JOURNAL
  doi: 10.1016/S0006-3495(84)84152-1
– volume: 321
  start-page: 406
  year: 1986
  ident: e_1_2_1_27_1
  publication-title: NATURE
  doi: 10.1038/321406a0
– volume: 307
  start-page: 604
  year: 1984
  ident: e_1_2_1_26_1
  publication-title: NATURE
  doi: 10.1038/307604a0
– volume: 76
  start-page: 2072
  year: 1979
  ident: e_1_2_1_30_1
  publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
– volume: 7
  start-page: 1792
  year: 1987
  ident: e_1_2_1_18_1
  publication-title: JOURNAL OF NEUROSCIENCE
  doi: 10.1523/JNEUROSCI.07-06-01792.1987
– volume: 81
  start-page: 155
  year: 1984
  ident: e_1_2_1_10_1
  publication-title: Proceedings of the National Academy of Sciences of the United States of America
– volume: 75
  start-page: 1016
  year: 1978
  ident: e_1_2_1_8_1
  publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
– volume: 327
  start-page: 515
  year: 1987
  ident: e_1_2_1_39_1
  publication-title: NATURE
  doi: 10.1038/327515a0
– volume: 324
  start-page: 670
  year: 1986
  ident: e_1_2_1_20_1
  publication-title: NATURE
  doi: 10.1038/324670a0
– volume: 26
  start-page: 2410
  year: 1987
  ident: e_1_2_1_11_1
  publication-title: BIOCHEMISTRY
  doi: 10.1021/bi00383a003
– volume: 48
  start-page: 965
  year: 1987
  ident: e_1_2_1_12_1
  publication-title: CELL
  doi: 10.1016/0092-8674(87)90705-7
– start-page: 417
  year: 1986
  ident: e_1_2_1_28_1
  publication-title: Nicotinic Acetylcholine Receptor: Structure and Function
– volume: 315
  start-page: 761
  year: 1985
  ident: e_1_2_1_35_1
  publication-title: NATURE
  doi: 10.1038/315761a0
– volume: 75
  start-page: 4853
  year: 1978
  ident: e_1_2_1_7_1
  publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
– volume: 74
  start-page: 3642
  year: 1977
  ident: e_1_2_1_25_1
  publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
– volume: 5
  start-page: 2545
  year: 1985
  ident: e_1_2_1_3_1
  publication-title: JOURNAL OF NEUROSCIENCE
  doi: 10.1523/JNEUROSCI.05-09-02545.1985
– ident: e_1_2_1_36_1
  doi: 10.1093/nar/14.11.4683
– volume: 205
  start-page: 137
  year: 1986
  ident: e_1_2_1_19_1
  publication-title: FEBS LETTERS
  doi: 10.1016/0014-5793(86)80881-X
– volume: 252
  start-page: 8629
  year: 1977
  ident: e_1_2_1_29_1
  publication-title: JOURNAL OF BIOLOGICAL CHEMISTRY
  doi: 10.1016/S0021-9258(19)75267-3
– volume: 259
  start-page: 11662
  year: 1984
  ident: e_1_2_1_21_1
  publication-title: JOURNAL OF BIOLOGICAL CHEMISTRY
  doi: 10.1016/S0021-9258(20)71257-3
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Snippet A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNA and complementary DNA encoding...
A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Experimental results demonstrate that the...
A new type of agonist-binding subunit of rat neuronal nicotinic acetylcholine receptors (nAChRs) was identified. Rat genomic DNa and complementary DNA encoding...
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StartPage 330
SubjectTerms acetylcholine
Amino Acid Sequence
Amino acid sequencing
Amino acids
Analysis
Animals
Base Sequence
Biochemistry
Biological and medical sciences
Brain
Brain - metabolism
Cell lines
Cell receptors
Cell structures and functions
Complementary DNA
DNA
DNA Restriction Enzymes
Exons
Female
Fundamental and applied biological sciences. Psychology
Gene expression
Generally accepted auditing standards
Genes
Genetics
Genomics
Medical research
Messenger RNA
Molecular and cellular biology
Molecular Sequence Data
Neurons - metabolism
Neurotransmitter receptors
Nucleotide Mapping
Oocytes
Oocytes - metabolism
Protein research
Rats
Receptors
Receptors, Nicotinic - genetics
Receptors, Nicotinic - metabolism
Transcription, Genetic
Xenopus laevis
Title Functional Expression of a New Pharmacological Subtype of Brain Nicotinic Acetylcholine Receptor
URI https://www.jstor.org/stable/1701604
https://www.ncbi.nlm.nih.gov/pubmed/2832952
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Volume 240
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