Single nucleotide polymorphism analysis in interstitial cystitis/painful bladder syndrome

• Published in: PloS one Vol. 14; no. 4; p. e0215201
• Main Authors: Cassão, Valter D., Reis, Sabrina T., Pimenta, Ruan, Lucon, Marcos, Leite, Katia R. M., Srougi, Miguel, Bruschini, Homero
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 11.04.2019; Public Library of Science (PLoS)
• Subjects: Alleles; Analysis; Biological markers; Biology and Life Sciences; Biomarkers; Bladder; Care and treatment; Case-Control Studies; Chronic pain; Chronic Pain - genetics; Chronic Pain - physiopathology; Comorbidity; Control methods; Cystitis; Cystitis, Interstitial - genetics; Cystitis, Interstitial - physiopathology; Disease control; Etiology; Etiology (Medicine); Female; Fibromyalgia; Gene Frequency; Genetic aspects; Genetic Markers; Genetic polymorphisms; Genetics; Genotype; Genotyping; Hospitals; Humans; Incontinence; Interstitial cystitis; Kidney diseases; Laboratories; Medical research; Medical schools; Medicine and Health Sciences; Middle Aged; Narcotics; Pain; Pain management; Pathogenesis; Patients; Pelvic pain; Pelvic Pain - genetics; Pelvic Pain - physiopathology; Polymorphism; Polymorphism, Single Nucleotide; Research and Analysis Methods; Signs and symptoms; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Systematic review; Urinary incontinence; Urology; Brazil

Interstitial Cystitis (IC) is a chronic condition diagnosed based on the presence of symptoms, such as suprapubic/ pelvic pain, pressure or discomfort in association with urgency and increased urinary frequency. Confusable diseases must be excluded. However, there is no objective test or marker to e...