High-Affinity Glucose Transport in Aspergillus nidulans Is Mediated by the Products of Two Related but Differentially Expressed Genes

• Published in: PloS one Vol. 9; no. 4; p. e94662
• Main Authors: Forment, Josep V., Flipphi, Michel, Ventura, Luisa, González, Ramón, Ramón, Daniel, MacCabe, Andrew P.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.04.2014; Public Library of Science (PLoS)
• Subjects: Affinity; Aspergillus; Aspergillus nidulans; Aspergillus nidulans - genetics; Aspergillus nidulans - metabolism; Biological transport; Biological Transport - genetics; Biology and Life Sciences; Blotting, Northern; Carbon; Catabolite repression; Catabolite Repression - genetics; Conidia; DNA damage; Energy Metabolism - genetics; Fungal Proteins - genetics; Fungal Proteins - metabolism; Fungi; Gene expression; Gene Expression Regulation, Fungal; Genes; Genes, Fungal; Genetic aspects; Genomes; Genotype; Germination; Glucose; Glucose - metabolism; Glucose transport; Glucose Transport Proteins, Facilitative - genetics; Glucose Transport Proteins, Facilitative - metabolism; Glucose transporter; Hyphae; Molecular Sequence Data; Mutation; Mutation - genetics; Phylogeny; Physiological aspects; Proteins; Research and Analysis Methods; Saccharomyces cerevisiae; Spores, Fungal - genetics; Starvation; Substrate Specificity; Transporter; Spain
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0094662

Independent systems of high and low affinity effect glucose uptake in the filamentous fungus Aspergillus nidulans. Low-affinity uptake is known to be mediated by the product of the mstE gene. In the current work two genes, mstA and mstC, have been identified that encode high-affinity glucose transpo...