Detection of novel polyomaviruses, TSPyV, HPyV6, HPyV7, HPyV9 and MWPyV in feces, urine, blood, respiratory swabs and cerebrospinal fluid

• Published in: PloS one Vol. 8; no. 5; p. e62764
• Main Authors: Rockett, Rebecca J, Sloots, Theo P, Bowes, Sharleen, O'Neill, Nicholas, Ye, Suifang, Robson, Jenny, Whiley, David M, Lambert, Stephen B, Wang, David, Nissen, Michael D, Bialasiewicz, Seweryn
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.05.2013; Public Library of Science (PLoS)
• Subjects: Adult; Adults; Biology; Blood; Blood - virology; Cerebrospinal fluid; Cerebrospinal Fluid - virology; Child; Children; Deoxyribonucleic acid; Diagnostic systems; DNA; DNA sequencing; Feces; Feces - virology; Gene sequencing; Genome, Viral - genetics; Genomes; Genomics; Health aspects; Humans; Immunocompromised hosts; Infections; Infectious diseases; Laboratories; Medical research; Medicine; Pathology; Patients; Pediatrics; Polyomavirus - genetics; Polyomavirus Infections - epidemiology; Polyomavirus Infections - genetics; Prevalence; Queensland - epidemiology; Real-Time Polymerase Chain Reaction; Respiration; Respiratory System - virology; Sequence Analysis, DNA; Shedding; Species Specificity; Studies; Subclinical infection; Tropism; Urine; Urine - virology; Virology; Viruses; Queensland; Queensland Australia

Eight novel human polyomaviruses have been discovered since 2007. Prevalence rates and tissue tropism for the most recent members HPyV 6, 7, 9, TSPyV and MWPyV are largely unknown. We used real-time PCR to determine the presence of HPyV 6, 7, 9, TSPyV and MWPyV in feces (n = 263), urine (n = 189), b...