Self-referent MHC type matching in frog tadpoles

• Published in: Proceedings of the Royal Society. B, Biological sciences Vol. 275; no. 1639; pp. 1225 - 1230
• Main Authors: Villinger, Jandouwe, Waldman, Bruce
• Format: Journal Article
• Language: English
• Published: London The Royal Society 22.05.2008
• Subjects: Altruism; Animals; Frogs; Genetic Linkage; Genetic loci; Genotype; Haplotypes; Human genetics; Immunology; Kin Recognition; Larva - genetics; Major Histocompatibility Complex; Major Histocompatibility Complex - genetics; Phenotype Matching; Polymerase chain reaction; Polymorphism, Genetic; Recognition Alleles; Siblings; Social discrimination; Tadpoles; Vertebrates; Xenopus laevis - genetics

Self/non-self recognition mechanisms underlie the development, immunology and social behaviour of virtually all living organisms, from bacteria to humans. Indeed, recognition processes lie at the core of how social cooperation evolved. Much evidence suggests that the major histocompatibility complex...