Emergence of Pathogenic Coronaviruses in Cats by Homologous Recombination between Feline and Canine Coronaviruses

• Published in: PloS one Vol. 9; no. 9; p. e106534
• Main Authors: Terada, Yutaka, Matsui, Nobutaka, Noguchi, Keita, Kuwata, Ryusei, Shimoda, Hiroshi, Soma, Takehisa, Mochizuki, Masami, Maeda, Ken
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 02.09.2014; Public Library of Science (PLoS)
• Subjects: Animals; Antibodies, Neutralizing - blood; Antibodies, Viral - blood; Biology and Life Sciences; Cat Diseases - virology; Cats; Cell culture; Comparative analysis; Coronaviridae; Coronavirus Infections - veterinary; Coronavirus Infections - virology; Coronavirus, Canine - classification; Coronavirus, Canine - genetics; Coronavirus, Canine - pathogenicity; Coronavirus, Feline - classification; Coronavirus, Feline - genetics; Coronavirus, Feline - pathogenicity; Coronaviruses; COVID-19; Disease; DNA, Viral - genetics; Dogs; Domestic cats; Emergence; Genes; Genes, Viral; Genomes; Homologous Recombination; Homology; Infections; Japan; Laboratories; Molecular Sequence Data; Mutation; Phylogeny; Proteins; Reassortant Viruses - genetics; Reassortant Viruses - pathogenicity; Sequence Homology, Nucleic Acid; Veterinary medicine; Viruses; Japan; Poland

Type II feline coronavirus (FCoV) emerged via double recombination between type I FCoV and type II canine coronavirus (CCoV). In this study, two type I FCoVs, three type II FCoVs and ten type II CCoVs were genetically compared. The results showed that three Japanese type II FCoVs, M91-267, KUK-H/L a...