Artery Wall Assessment Helps Predict Kidney Transplant Outcome

• Published in: PloS one Vol. 10; no. 6; p. e0129083
• Main Authors: Hernández, Domingo, Triñanes, Javier, Salido, Eduardo, Pitti, Sergio, Rufino, Margarita, González-Posada, José Manuel, Torres, Armando
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 12.06.2015; Public Library of Science (PLoS)
• Subjects: Adhesion tests; Adult; Analysis; Atherosclerosis; Bivariate analysis; Blood pressure; Calcification; Calcification (ectopic); Cardiovascular diseases; Carotid Intima-Media Thickness; Cell adhesion & migration; Cytokines; Diabetes; Diabetes mellitus; Disease; Female; Gene expression; Glucose; Health aspects; Health risks; Hospitals; Humans; Inflammation; Kidney transplantation; Kidney Transplantation - mortality; Kidney transplants; Kidneys; Male; Medical research; Middle Aged; Molecular chains; Mortality; Mortality risk; Multiple regression analysis; Nephrology; Observational studies; Organ transplant recipients; Patients; Predictive Value of Tests; Prognosis; Proteins; Regression analysis; Risk analysis; Risk factors; Smoking; Survival; Survival Rate; Transplantation; Transplants & implants; Triglycerides; Tunica Intima - diagnostic imaging; Tunica Intima - metabolism; Ultrasonic imaging; Vascular cell adhesion molecule 1; Vascular Cell Adhesion Molecule-1 - metabolism; Veins & arteries; Japan; Tenerife; Spain

Kidney transplant recipients have high cardiovascular risk, and vascular inflammation may play an important role. We explored whether the inflammatory state in the vessel wall was related to carotid intima-media thickness (c-IMT) and patient survival following kidney transplantation. In this prospec...