Brain Viscoelasticity Alteration in Chronic-Progressive Multiple Sclerosis

• Published in: PloS one Vol. 7; no. 1; p. e29888
• Main Authors: Streitberger, Kaspar-Josche, Sack, Ingolf, Krefting, Dagmar, Pfüller, Caspar, Braun, Jürgen, Paul, Friedemann, Wuerfel, Jens
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 20.01.2012; Public Library of Science (PLoS)
• Subjects: Adult; Autoimmune diseases; Automation; Biology; Biomechanics; Brain; Brain - pathology; Brain - physiopathology; Brain damage; Brain research; Disease; Elasticity; Elasticity - physiology; Elasticity Imaging Techniques; Encephalitis; Female; Histopathology; Humans; Hypotheses; In vivo methods and tests; Inflammation; Magnetic resonance; Male; Medical imaging equipment; Medical research; Medicine; Middle Aged; Multiple sclerosis; Multiple Sclerosis, Chronic Progressive - pathology; NMR; Nuclear magnetic resonance; Parenchyma; Patients; Registration; Rheology; Studies; Tissues; Viscoelasticity; Viscosity; Germany

Viscoelastic properties indicate structural alterations in biological tissues at multiple scales with high sensitivity. Magnetic Resonance Elastography (MRE) is a novel technique that directly visualizes and quantitatively measures biomechanical tissue properties in vivo. MRE recently revealed that...