Gene Expression Profiling of the Local Cecal Response of Genetic Chicken Lines That Differ in Their Susceptibility to Campylobacter jejuni Colonization

• Published in: PloS one Vol. 5; no. 7; p. e11827
• Main Authors: Li, Xianyao, Swaggerty, Christina L., Kogut, Michael H., Chiang, Hsin-I, Wang, Ying, Genovese, Kenneth J., He, Haiqi, Zhou, Huaijun
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 28.07.2010; Public Library of Science (PLoS)
• Subjects: Activation; Agriculture; amino acid metabolism; Amino acids; animal pathogenic bacteria; Animals; Bacteria; bacterial colonization; bacterial enteritis; biochemical pathways; Birds; Campylobacter; Campylobacter jejuni; Campylobacter jejuni - growth & development; Cecum; Cecum - metabolism; Cecum - microbiology; Cell activation; Cell differentiation; Cell interactions; Chickens; Circadian rhythm; Circadian rhythms; Colonization; disease resistance; DNA microarrays; Dressed poultry; Enteritis; enteropathogens; Food contamination; Gene expression; Gene Expression Profiling; gene expression regulation; Genes; genetic lines; Genetics and Genomics/Animal Genetics; Genetics and Genomics/Functional Genomics; Genetics and Genomics/Gene Expression; Genomes; glucose; Glucose metabolism; host-pathogen relationships; immune response; Immunoregulation; Inoculation; Insulin; Intestine; lymphocyte proliferation; Lymphocytes; Lymphocytes T; Metabolism; microarray technology; Molecular modelling; Oligonucleotide Array Sequence Analysis; Pathogens; Pathways; Polymerase Chain Reaction; Poultry; poultry products; resistance mechanisms; Ribonucleic acid; RNA; Signal transduction; Signaling; T cells; T-lymphocytes; United States > US; Texas

Campylobacter jejuni (C. jejuni) is one of the most common causes of human bacterial enteritis worldwide primarily due to contaminated poultry products. Previously, we found a significant difference in C. jejuni colonization in the ceca between two genetically distinct broiler lines (Line A (resista...