In vitro factor XIII supplementation increases clot firmness in Rotation Thromboelastometry (ROTEM)

• Published in: Thrombosis and haemostasis Vol. 104; no. 2; p. 385
• Main Authors: Theusinger, Oliver M, Baulig, Werner, Asmis, Lars M, Seifert, Burkhardt, Spahn, Donat R
• Format: Journal Article
• Language: English
• Published: Germany 01.08.2010
• Subjects: Aged; Blood Coagulation; Critical Care; Factor XIII - metabolism; Factor XIII Deficiency - blood; Factor XIII Deficiency - diagnosis; Female; Fibrinogen - metabolism; Fibrinolysin; Hematocrit; Humans; Male; Middle Aged; Platelet Count; Postoperative Care; Predictive Value of Tests; Prospective Studies; Rotation; Switzerland; Thrombelastography - methods; Switzerland

Factor XIII (F XIII) is an essential parameter for final clot stability. The purpose of this study was to determine the impact of the addition of factor (F)XIII on clot stability as assessed by Rotation Thromboelastometry (ROTEM). In 90 intensive care patients ROTEM measurements were performed after...