Childhood tuberous sclerosis complex in southern Sweden: a paradigm shift in diagnosis and treatment

• Published in: BMC pediatrics Vol. 23; no. 1; pp. 329 - 11
• Main Authors: Pearsson, Kevin, Björk Werner, Josefin, Lundgren, Johan, Gränse, Lotta, Karlsson, Emma, Källén, Kristina, Eklund, Erik A., Bekassy, Zivile
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 29.06.2023; BioMed Central; BMC
• Subjects: Age; Angiomyolipoma; Angiomyolipoma, astrocytic hamartoma, cardiac rhabdomyoma, epilepsy, everolimus; Astrocytic hamartoma; Blood pressure; Cardiac arrhythmia; Cardiac rhabdomyoma; Care and treatment; Childhood; Children; Clinical Medicine; Convulsions & seizures; Diagnosis; Diseases; Electrocardiography; Epilepsy; Everolimus; Hydrocephalus; Inhibitor drugs; Intellectual disabilities; Klinisk medicin; Magnetic resonance imaging; Medical and Health Sciences; Medical diagnosis; Medicin och hälsovetenskap; Neurologi; Neurology; Pediatrics; Pediatrik; Surgery; Tuberous sclerosis; Tumors; Sweden; Angiomyolipoma; Everolimus; Cardiac rhabdomyoma; Epilepsy; Astrocytic hamartoma

To investigate the complete clinical spectrum of individuals with paediatric tuberous sclerosis complex in southern Sweden and explore changes over time. In this retrospective observational study, 52 individuals aged up to 18 years at the study start were followed-up at regional hospitals and centre...