Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22 - Schnepf, Daniel; Hernandez, Pedro; Mahlakõiv, Tanel; Crotta, Stefania; Sullender, Meagan E.; Peterson, Stefan T.; Ohnemus, Annette; Michiels, Camille; Gentle, Ian; Dumoutier, Laure; Reis, Celso A.; Diefenbach, Andreas; et al. (PloS one, 2021)
Keywords: Animal models; Animals; Anti-Bacterial Agents - adverse effects; Anti-Bacterial Agents - pharmacology; Antibiotics; Antiviral drugs; Apoptosis; Bacteria; Biology; Biosynthesis; Cell death; Complications and side effects; Crick, Francis; Cytokines; Development and progression; Disease Susceptibility; Female; Gastrointestinal Microbiome - drug effects; Gene Expression Profiling; Genomes; Germfree; Health aspects; Immune response; Immunology; Infections; Infectious diseases; Innate immunity; Interferon; Interleukin; Interleukin 22; Interleukins; Interleukins - metabolism; Interleukins - physiology; Intestinal Mucosa - metabolism; Intestine; Laboratories; Life Sciences; Male; Medicine; Mice; Mice, Inbred C57BL; Mice, Knockout; Microbiomes; Microbiota; Microbiota (Symbiotic organisms); Mucosal immunity; Necroptosis; Pathogens; Physiological aspects; Polysaccharides; Probiotics; Pyroptosis; Real-Time Polymerase Chain Reaction; Replication; Risk factors; Rotavirus; Rotavirus - physiology; Rotavirus infections; Rotavirus Infections - etiology; Small intestine; Stat1 protein; Supervision; Susceptibility; Viral infections; Virology; Viruses; Germany; United Kingdom--UK; Belgium; St Louis Missouri; United States--US; Portugal