Involvement of Nt ERF 3 in the cell death signalling pathway mediated by SIPK / WIPK and WRKY 1 in tobacco plants
Abstract We previously reported that one of the ethylene response factors ( ERF s), Nt ERF 3, and other members of the subgroup VIII ‐a ERF s of the AP 2/ ERF family exhibit cell death‐inducing ability in tobacco leaves. In this study, we focused on the involvement of Nt ERF 3 in a cell death signal...
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| Published in | Plant biology (Stuttgart, Germany) Vol. 17; no. 5; pp. 962 - 972 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
01.09.2015
|
| Online Access | Get full text |
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| Abstract | Abstract
We previously reported that one of the ethylene response factors (
ERF
s), Nt
ERF
3, and other members of the subgroup
VIII
‐a
ERF
s of the
AP
2/
ERF
family exhibit cell death‐inducing ability in tobacco leaves. In this study, we focused on the involvement of Nt
ERF
3 in a cell death signalling pathway in tobacco plants, particularly downstream of Nt
SIPK
/Nt
WIPK
and Nt
WRKY
1, which are mitogen‐activated protein kinases and a phosphorylation substrate of Nt
SIPK
, respectively. An
ERF
‐associated amphiphilic repression (
EAR
) motif‐deficient
Nt
ERF
3b
mutant (
Nt
ERF
3bΔ
EAR
) that lacked cell death‐inducing ability suppressed the induction of cell death caused by
Nt
ERF
3a
. The transient co‐expression of
Nt
ERF
3bΔ
EAR
suppressed the hypersensitive reaction (
HR
)‐like cell death induced by
Nt
SIPK
and
Nt
WRKY
1
. The induction of cell death by
Nt
SIPK
and
Nt
WRKY
1
was also inhibited in transgenic plants expressing
Nt
ERF
3bΔ
EAR
. Analysis of gene expression, ethylene production and cell death symptoms in salicylic acid‐deficient tobacco plants suggested the existence of some feedback regulation in the
HR
cell death signalling pathway mediated by
SIPK
/
WIPK
and
WRKY
1. Overall, these results suggest that
Nt
ERF
3
functions downstream of
Nt
SIPK
/
Nt
WIPK
and
Nt
WRKY
1
in a cell death signalling pathway, with some feedback regulation. |
|---|---|
| AbstractList | Abstract
We previously reported that one of the ethylene response factors (
ERF
s), Nt
ERF
3, and other members of the subgroup
VIII
‐a
ERF
s of the
AP
2/
ERF
family exhibit cell death‐inducing ability in tobacco leaves. In this study, we focused on the involvement of Nt
ERF
3 in a cell death signalling pathway in tobacco plants, particularly downstream of Nt
SIPK
/Nt
WIPK
and Nt
WRKY
1, which are mitogen‐activated protein kinases and a phosphorylation substrate of Nt
SIPK
, respectively. An
ERF
‐associated amphiphilic repression (
EAR
) motif‐deficient
Nt
ERF
3b
mutant (
Nt
ERF
3bΔ
EAR
) that lacked cell death‐inducing ability suppressed the induction of cell death caused by
Nt
ERF
3a
. The transient co‐expression of
Nt
ERF
3bΔ
EAR
suppressed the hypersensitive reaction (
HR
)‐like cell death induced by
Nt
SIPK
and
Nt
WRKY
1
. The induction of cell death by
Nt
SIPK
and
Nt
WRKY
1
was also inhibited in transgenic plants expressing
Nt
ERF
3bΔ
EAR
. Analysis of gene expression, ethylene production and cell death symptoms in salicylic acid‐deficient tobacco plants suggested the existence of some feedback regulation in the
HR
cell death signalling pathway mediated by
SIPK
/
WIPK
and
WRKY
1. Overall, these results suggest that
Nt
ERF
3
functions downstream of
Nt
SIPK
/
Nt
WIPK
and
Nt
WRKY
1
in a cell death signalling pathway, with some feedback regulation. |
| Author | Seo, S. Matsushita, Y. Okada, H. Ogata, T. Kawaide, H. Takahashi, H. Mitsuhara, I. |
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| CitedBy_id | crossref_primary_10_1093_plphys_kiac171 crossref_primary_10_3389_fpls_2020_582208 crossref_primary_10_1007_s10327_018_0762_y crossref_primary_10_1007_s12298_016_0402_y crossref_primary_10_1093_jxb_erad451 crossref_primary_10_1080_09583157_2018_1514585 crossref_primary_10_5010_JPB_2017_44_3_220 crossref_primary_10_3389_fpls_2017_00150 crossref_primary_10_1016_j_plantsci_2021_111149 crossref_primary_10_3389_fpls_2020_01235 crossref_primary_10_1111_plb_13411 crossref_primary_10_3389_fpls_2020_00879 crossref_primary_10_1016_j_jplph_2017_05_002 |
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We previously reported that one of the ethylene response factors (
ERF
s), Nt
ERF
3, and other members of the subgroup
VIII
‐a
ERF
s of the
AP
2/
ERF... |
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| Title | Involvement of Nt ERF 3 in the cell death signalling pathway mediated by SIPK / WIPK and WRKY 1 in tobacco plants |
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