A Fast and Validated HPLC Method for Simultaneous Determination of Dopamine, Dobutamine, Phentolamine, Furosemide, and Aminophylline in Infusion Samples and Injection Formulations

• Published in: Journal of analytical methods in chemistry Vol. 2021; pp. 1 - 9
• Main Authors: Chen, Fuchao, Fang, Baoxia, Wang, Sicen
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 2021; John Wiley & Sons, Inc; Wiley
• Subjects: Acetonitrile; Aminophylline; Analysis; Cardiac glycosides; Cardiotonic agents; chemical species; chemistry; detection limit; Diuretics; Dopamine; Dosage; dosage forms; Drug dosages; Drugs; Flow velocity; Formulations; Furosemide; glucose; High performance liquid chromatography; Linearity; Membrane filters; Methods; Pharmaceuticals; Phenols; polypropylenes; Potassium phosphates; Quality control; Quality standards; Sodium chloride; Stability analysis; Sympathomimetic agents; temperature; China; Beijing China; United States > US
• ISSN: 2090-8865; 2090-8873; 2090-8873
• DOI: 10.1155/2021/8821126

A simple, fast, and validated HPLC method was developed for the simultaneous quantization of five cardiovascular agents: dopamine (DPM), dobutamine (DBM), phentolamine (PTM), furosemide (FSM), and aminophylline (APL) either in infusion samples or in an injection dosage form. The proposed method was...