Longitudinal changes in 18 F‐ THK 5351 positron emission tomography in corticobasal syndrome

• Published in: European journal of neurology Vol. 26; no. 9; pp. 1205 - 1211
• Main Authors: Ezura, M., Kikuchi, A., Ishiki, A., Okamura, N., Hasegawa, T., Harada, R., Watanuki, S., Funaki, Y., Hiraoka, K., Baba, T., Sugeno, N., Oshima, R., Yoshida, S., Kobayashi, J., Kobayashi, M., Tano, O., Nakashima, I., Mugikura, S., Iwata, R., Taki, Y., Furukawa, K., Arai, H., Furumoto, S., Tashiro, M., Yanai, K., Kudo, Y., Takeda, A., Aoki, M.
• Format: Journal Article
• Language: English
• Published: 01.09.2019

Background and purpose Corticobasal syndrome ( CBS ) is pathologically characterized by tau deposits in neuronal and glial cells and by reactive astrogliosis. In several neurodegenerative disorders, 18 F‐ THK 5351 has been observed to bind to reactive astrocytes expressing monoamine oxidase B. In th...