Geographic distribution of the 20210 G to A prothrombin variant

• Published in: Thrombosis and haemostasis Vol. 79; no. 4; p. 706
• Main Authors: Rosendaal, F R, Doggen, C J, Zivelin, A, Arruda, V R, Aiach, M, Siscovick, D S, Hillarp, A, Watzke, H H, Bernardi, F, Cumming, A M, Preston, F E, Reitsma, P H
• Format: Journal Article
• Language: English
• Published: Germany 1998
• Subjects: Brazil - epidemiology; Ethnic Groups - genetics; Europe - epidemiology; Gene Frequency; Genetic Carrier Screening; Humans; Point Mutation; Prothrombin - genetics; Thrombophilia - epidemiology; Thrombophilia - genetics; United States - epidemiology

A variant in prothrombin (clotting factor II), a G to A transition at nucleotide position 20210, has recently been shown to be associated with the prothrombin plasma levels and the risk of both venous and arterial thrombosis. The purpose of this study was to investigate the prevalence of carriership...